Elevated β1-Adrenergic Receptor Autoantibody Levels Increase Atrial Fibrillation Susceptibility by Promoting Atrial Fibrosis

Elevated β1-Adrenergic Receptor Autoantibody Levels Increase Atrial Fibrillation Susceptibility by Promoting Atrial Fibrosis

ObjectiveBeta 1-adrenergic receptor autoantibodies (β1ARAbs) have been identified as a pathogenic factor in atrial fibrillation (AF), but the underlying pathogenetic mechanism is not well understood. We assessed the hypothesis that elevated β1ARAb levels increase AF susceptibility by promoting atria...

Full description

Bibliographic Details
Main Authors:	Luxiang Shang, Ling Zhang, Mengjiao Shao, Min Feng, Jia Shi, Zhenyu Dong, Qilong Guo, Jiasuoer Xiaokereti, Ran Xiang, Huaxin Sun, Xianhui Zhou, Baopeng Tang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-02-01
Series:	Frontiers in Physiology
Subjects:	atrial fibrillation β1-adrenergic receptor autoantibody atrial fibrosis circulating fibrosis biomarker autoimmune
Online Access:	https://www.frontiersin.org/article/10.3389/fphys.2020.00076/full

Similar Items

Autoantibodies in Atrial Fibrillation—State of the Art
by: Joanna Zygadło, et al.
Published: (2023-01-01)

Low-Level Vagus Nerve Stimulation Reverses Obstructive Sleep Apnea-Related Atrial Fibrillation by Ameliorating Sympathetic Hyperactivity and Atrial Myocyte Injury
by: Yankai Guo, et al.
Published: (2021-01-01)

Apelin Inhibits Angiotensin II-Induced Atrial Fibrosis and Atrial Fibrillation via TGF-β1/Smad2/α-SMA Pathway
by: Wenkui Lv, et al.
Published: (2020-11-01)

Atrial fibrillation and miRNA
by: Cao Peng
Published: (2023-01-01)

Myocardial fibrosis during atrial fibrillation: histological and cardiographic predictors
by: R.F. Rakhmatullov, et al.
Published: (2023-12-01)

Pathogenic Mechanisms of Atrial Fibrillation in Obesity
by: O. M. Drapkina, et al.
Published: (2016-11-01)

Elevated Circulating Fibrocytes Is a Marker of Left Atrial Fibrosis and Recurrence of Persistent Atrial Fibrillation
by: Yang Liu, et al.
Published: (2018-03-01)

ATRIAL FIBROSIS IS A MORPHOLOGICAL BASIS OF ATRIAL FIBRILLATION
by: O. M. Drapkina, et al.
Published: (2015-09-01)

Impaired left atrial reservoir and conduit strain in patients with atrial fibrillation and extensive left atrial fibrosis
by: Luuk H. G. A. Hopman, et al.
Published: (2021-11-01)

The emerging role of ferroptosis in myocardial fibrosis of atrial fibrillation
by: Honghua Yue, et al.
Published: (2023-02-01)

Myocardial Fibrosis and the Risk of Recurrence in Atrial Fibrillation
by: Kovács István, et al.
Published: (2016-12-01)

Mechanisms and Management of Thyroid Disease and Atrial Fibrillation: Impact of Atrial Electrical Remodeling and Cardiac Fibrosis
by: Abhijit Takawale, et al.
Published: (2022-12-01)

Cadherin-11 Deficiency Attenuates Ang-II-Induced Atrial Fibrosis and Susceptibility to Atrial Fibrillation
by: Cao W, et al.
Published: (2021-07-01)

Galectin-3 in patients with atrial fibrillation and restored sinus rhythm
by: Antoniya Kisheva, et al.
Published: (2021-06-01)

New Strategies for the Treatment of Atrial Fibrillation
by: Norbert Jost, et al.
Published: (2021-09-01)

Regional and temporal progression of atrial remodeling in angiotensin II mediated atrial fibrillation
by: Hailey J. Jansen, et al.
Published: (2022-11-01)

Left atrial strain predicts fibrosis of left atrial appendage in patients with atrial fibrillation undergoing totally thoracoscopic ablation
by: Jihoon Kim, et al.
Published: (2023-05-01)

The role of the structural fibrosis markers in the left atrial remodeling in patients with paroxymal atrial fibrillation
by: A. I. Gozhenko, et al.
Published: (2017-02-01)

The role of the structural fibrosis markers in the left atrial remodeling in patients with paroxymal atrial fibrillation
by: A. I. Gozhenko, et al.
Published: (2017-02-01)

Ganglionated Plexi Ablation Suppresses Chronic Obstructive Sleep Apnea-Related Atrial Fibrillation by Inhibiting Cardiac Autonomic Hyperactivation
by: Ling Zhang, et al.
Published: (2021-04-01)

Heart Failure, Female Sex, and Atrial Fibrillation Are the Main Drivers of Human Atrial Cardiomyopathy: Results From the CATCH ME Consortium
by: Joris Winters, et al.
Published: (2023-11-01)

Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice
by: Ya Suo, et al.
Published: (2019-10-01)

The expression profile analysis of atrial mRNA in rats with atrial fibrillation: the role of IGF1 in atrial fibrosis
by: Jiangrong Wang, et al.
Published: (2019-02-01)

Isoproterenol Increases Left Atrial Fibrosis and Susceptibility to Atrial Fibrillation by Inducing Atrial Ischemic Infarction in Rats
by: Shiyu Ma, et al.
Published: (2020-04-01)

Extensive atrial fibrosis in a patient with systemic lupus erythematosus and atrial fibrillation
by: Elena Costanza dal Piaz, MD, et al.
Published: (2015-07-01)

Beyond the Rhythm: In Silico Identification of Key Genes and Therapeutic Targets in Atrial Fibrillation
by: Natalia Atzemian, et al.
Published: (2023-09-01)

microRNAs as Biomarkers of Endothelial Dysfunction and Therapeutic Target in the Pathogenesis of Atrial Fibrillation
by: Vanessa Desantis, et al.
Published: (2023-03-01)

Fibrotic Remodeling during Persistent Atrial Fibrillation: In Silico Investigation of the Role of Calcium for Human Atrial Myofibroblast Electrophysiology
by: Jorge Sánchez, et al.
Published: (2021-10-01)

Left Atrial Structural Remodelling in Non-Valvular Atrial Fibrillation: What Have We Learnt from CMR?
by: Mariana Floria, et al.
Published: (2020-03-01)

Increased plasma microfibrillar-associated protein 4 is associated with atrial fibrillation and more advanced left atrial remodelling
by: Xianlin Zhang, et al.
Published: (2018-04-01)

Role of Inflammation in the Pathogenesis of Atrial Fibrillation
by: Kensuke Ihara, et al.
Published: (2022-04-01)

Aging‐induced atrial fibrosis in If current change and its effect on atrial fibrillation in dogs
by: Fei‐Fei Wang, et al.
Published: (2022-07-01)

Research Progress of Low-Voltage Areas Associated with Atrial Fibrillation
by: Yunfei Gu, et al.
Published: (2023-11-01)

Atrial Fibrillation Promotion in a Rat Model of Rheumatoid Arthritis
by: Hui Dai, et al.
Published: (2017-12-01)

Role of Monocytes in Heart Failure and Atrial Fibrillation
by: Farhan Shahid, et al.
Published: (2018-02-01)

Imaging Techniques for the Study of Fibrosis in Atrial Fibrillation Ablation: From Molecular Mechanisms to Therapeutical Perspectives
by: Francesco De Sensi, et al.
Published: (2021-05-01)

Cardiac-specific knockdown of Bhlhe40 attenuates angiotensin II (Ang II)-Induced atrial fibrillation in mice
by: Kai-Wen Ren, et al.
Published: (2022-10-01)

Presence of Left Atrial Fibrosis May Contribute to Aberrant Hemodynamics and Increased Risk of Stroke in Atrial Fibrillation Patients
by: Nikhil Paliwal, et al.
Published: (2021-06-01)

Effect of catheter ablation for atrial fibrillation on left and right atrial function
by: T. V. Moskovskikh, et al.
Published: (2022-08-01)

Long-Term Changes in the Biomarkers of Left Atrial Fibrosis after Pulmonary Vein Isolation for Paroxysmal and Persistent Atrial Fibrillation
by: Lilla Szuromi, et al.
Published: (2023-06-01)