The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review
As the coronavirus disease 2019 (COVID-19) pandemic continues worldwide, vaccination has been considered an effective measure to protect people from the COVID-19 and end the pandemic. However, for patients with rheumatic diseases (RD), concern for the induction of RD flare may combat the enthusiasm...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2022.919979/full |
| _version_ | 1811323836376809472 |
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| author | Yan Xie Yang Liu Yi Liu |
| author_facet | Yan Xie Yang Liu Yi Liu |
| author_sort | Yan Xie |
| collection | DOAJ |
| description | As the coronavirus disease 2019 (COVID-19) pandemic continues worldwide, vaccination has been considered an effective measure to protect people from the COVID-19 and end the pandemic. However, for patients with rheumatic diseases (RD), concern for the induction of RD flare may combat the enthusiasm for vaccination. In general, current evidence doesn’t support the increased risk of disease flare after COVID-19 vaccination. However, the disease flare of RDs may be triggered by COVID-19 vaccinations, especially for patients with high disease activity. Most of these flares after vaccination are mild and need no treatment escalation. Considering the benefits and risks, RD patients are recommended to receive the COVID-19 vaccination but should be vaccinated when the RDs are in stable states. |
| first_indexed | 2024-04-13T14:03:26Z |
| format | Article |
| id | doaj.art-869d070b176d4219a86ef4b5afcf638e |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-04-13T14:03:26Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-869d070b176d4219a86ef4b5afcf638e2022-12-22T02:44:00ZengFrontiers Media S.A.Frontiers in Immunology1664-32242022-07-011310.3389/fimmu.2022.919979919979The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A ReviewYan Xie0Yang Liu1Yi Liu2Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, ChinaTsinghua Clinical Research Institute (TCRI), School of Medicine, Tsinghua University, Beijing, ChinaDepartment of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu, ChinaAs the coronavirus disease 2019 (COVID-19) pandemic continues worldwide, vaccination has been considered an effective measure to protect people from the COVID-19 and end the pandemic. However, for patients with rheumatic diseases (RD), concern for the induction of RD flare may combat the enthusiasm for vaccination. In general, current evidence doesn’t support the increased risk of disease flare after COVID-19 vaccination. However, the disease flare of RDs may be triggered by COVID-19 vaccinations, especially for patients with high disease activity. Most of these flares after vaccination are mild and need no treatment escalation. Considering the benefits and risks, RD patients are recommended to receive the COVID-19 vaccination but should be vaccinated when the RDs are in stable states.https://www.frontiersin.org/articles/10.3389/fimmu.2022.919979/fullCOVID-19SARS-CoV-2vaccinerheumatic diseaseflare |
| spellingShingle | Yan Xie Yang Liu Yi Liu The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review Frontiers in Immunology COVID-19 SARS-CoV-2 vaccine rheumatic disease flare |
| title | The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review |
| title_full | The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review |
| title_fullStr | The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review |
| title_full_unstemmed | The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review |
| title_short | The Flare of Rheumatic Disease After SARS-CoV-2 Vaccination: A Review |
| title_sort | flare of rheumatic disease after sars cov 2 vaccination a review |
| topic | COVID-19 SARS-CoV-2 vaccine rheumatic disease flare |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2022.919979/full |
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