Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors

Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors

Tick-borne encephalitis virus (TBEV), the most medically relevant tick-transmitted flavivirus in Eurasia, targets the host central nervous system and frequently causes severe encephalitis. The severity of TBEV-induced neuropathogenesis is highly cell-type specific and the exact mechanism responsible...

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Bibliographic Details
Main Authors: Martin Selinger, Pavlína Věchtová, Hana Tykalová, Petra Ošlejšková, Michaela Rumlová, Ján Štěrba, Libor Grubhoffer
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Alternative splicing
Astrocytes
miRNA
Neurons
Response to infection
Neuropathogenesis
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002070

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