Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes
Herpes simplex viruses (HSV-1 and HSV-2) contain up to 16 different proteins in their envelopes. Four of these, glycoproteins gB, gD, gH, and gL, are termed essential with regard to entry, whereas the rest are typically referred to as nonessential based on the entry phenotypes of the respective sing...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2021-04-01
|
| Series: | mBio |
| Online Access: | https://journals.asm.org/doi/10.1128/mBio.00143-21 |
| _version_ | 1818908276531658752 |
|---|---|
| author | Adam T. Hilterbrand Raecliffe E. Daly Ekaterina E. Heldwein |
| author_facet | Adam T. Hilterbrand Raecliffe E. Daly Ekaterina E. Heldwein |
| author_sort | Adam T. Hilterbrand |
| collection | DOAJ |
| description | Herpes simplex viruses (HSV-1 and HSV-2) contain up to 16 different proteins in their envelopes. Four of these, glycoproteins gB, gD, gH, and gL, are termed essential with regard to entry, whereas the rest are typically referred to as nonessential based on the entry phenotypes of the respective single genetic deletions. |
| first_indexed | 2024-12-19T22:08:27Z |
| format | Article |
| id | doaj.art-86a55c7f8305485fbd0e0189a9d8ac91 |
| institution | Directory Open Access Journal |
| issn | 2150-7511 |
| language | English |
| last_indexed | 2024-12-19T22:08:27Z |
| publishDate | 2021-04-01 |
| publisher | American Society for Microbiology |
| record_format | Article |
| series | mBio |
| spelling | doaj.art-86a55c7f8305485fbd0e0189a9d8ac912022-12-21T20:03:59ZengAmerican Society for MicrobiologymBio2150-75112021-04-0112210.1128/mBio.00143-21Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry RoutesAdam T. Hilterbrand0https://orcid.org/0000-0003-4221-6523Raecliffe E. Daly1Ekaterina E. Heldwein2https://orcid.org/0000-0003-3113-6958Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USADepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USADepartment of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, USAHerpes simplex viruses (HSV-1 and HSV-2) contain up to 16 different proteins in their envelopes. Four of these, glycoproteins gB, gD, gH, and gL, are termed essential with regard to entry, whereas the rest are typically referred to as nonessential based on the entry phenotypes of the respective single genetic deletions.https://journals.asm.org/doi/10.1128/mBio.00143-21 |
| spellingShingle | Adam T. Hilterbrand Raecliffe E. Daly Ekaterina E. Heldwein Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes mBio |
| title | Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes |
| title_full | Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes |
| title_fullStr | Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes |
| title_full_unstemmed | Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes |
| title_short | Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes |
| title_sort | contributions of the four essential entry glycoproteins to hsv 1 tropism and the selection of entry routes |
| url | https://journals.asm.org/doi/10.1128/mBio.00143-21 |
| work_keys_str_mv | AT adamthilterbrand contributionsofthefouressentialentryglycoproteinstohsv1tropismandtheselectionofentryroutes AT raecliffeedaly contributionsofthefouressentialentryglycoproteinstohsv1tropismandtheselectionofentryroutes AT ekaterinaeheldwein contributionsofthefouressentialentryglycoproteinstohsv1tropismandtheselectionofentryroutes |