Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells
Abstract Background This study was aimed at investigating whether metformin can reverse the resistance of ovarian cancer cells to cisplatin and exploring the underlying mechanism. Methods Ovarian cancer cell proliferation in vitro was evaluated using a CCK-8 assay. The resistance index of platinum-r...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-12-01
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| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12885-017-3840-1 |