Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study
INTRODUCTION: Tuberculosis (TB) remains a major cause of death in people living with HIV/AIDS (PLWHA). This study assessed TB burden and its predictors among PLWHA receiving care at the State Specialist Hospital, Osogbo, Nigeria. METHODS: A prospective study was conducted among PLWHA screened clini...
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| Format: | Article |
| Language: | English |
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Rwanda Biomedical Centre (RBC)/Rwanda Health Communication Center
2023-09-01
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| Series: | Rwanda Medical Journal |
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| _version_ | 1827792934629539840 |
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| author | S. A. Olowookere O. F. Awopeju F. O. Fehintola O. Arije T. O. Ojo O. I. Obe-Adeoye O. A. Aina M. O. Gbadamosi E. G. Adepoju |
| author_facet | S. A. Olowookere O. F. Awopeju F. O. Fehintola O. Arije T. O. Ojo O. I. Obe-Adeoye O. A. Aina M. O. Gbadamosi E. G. Adepoju |
| author_sort | S. A. Olowookere |
| collection | DOAJ |
| description | INTRODUCTION: Tuberculosis (TB) remains a major cause of death in people living with HIV/AIDS (PLWHA). This study assessed TB burden and its predictors among PLWHA receiving care at the State Specialist Hospital, Osogbo, Nigeria.
METHODS: A prospective study was conducted among PLWHA screened clinically for TB from February 2009 till December 2019. Information collected included their socio-demographic characteristics, other variables, TB signs and symptoms, and CD4 count. PLWHA with at least one TB symptom or sign underwent laboratory diagnosis. Data were analyzed using descriptive and inferential statistics.
RESULTS: A total of 4057 PLWHA were screened clinically for TB during the study period. They were 982 (24.2%) males and 3075 (75.8%) females. Six hundred and ninety-eight (33.4%) were diagnosed with TB. On logistic regression analysis, predictors of TB included being female (AOR=3.53, 95%CI=2.72-4.59, p<0.001), having lower education (AOR=2.53, 95%CI=2.07-3.10, p<0.001), having low socio-economic status (AOR=34.54, 95%CI=21.10-56.52, p=0.0001), being underweight (AOR=3.28, 95%CI=2.69-4.10, p<0.001) and having CD4 count <200/ml (AOR=3.69, 95%CI=3.04-4.47, p<0.001).
CONCLUSION: PLWHA had a high TB burden with predictors including low socio-economic status, being female, having had lower education, low CD4 count, and being underweight. Addressing these factors may reduce the TB burden among PLWHA. |
| first_indexed | 2024-03-11T18:11:18Z |
| format | Article |
| id | doaj.art-86abd5a35d744c108abc4fc23e1495bf |
| institution | Directory Open Access Journal |
| issn | 2410-8626 |
| language | English |
| last_indexed | 2024-03-11T18:11:18Z |
| publishDate | 2023-09-01 |
| publisher | Rwanda Biomedical Centre (RBC)/Rwanda Health Communication Center |
| record_format | Article |
| series | Rwanda Medical Journal |
| spelling | doaj.art-86abd5a35d744c108abc4fc23e1495bf2023-10-16T14:15:49ZengRwanda Biomedical Centre (RBC)/Rwanda Health Communication CenterRwanda Medical Journal2410-86262023-09-018034248https://dx.doi.org/10.4314/rmj.v80i3.6Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective studyS. A. Olowookere0O. F. Awopeju1F. O. Fehintola2O. Arije3T. O. Ojo4O. I. Obe-Adeoye5O. A. Aina6 M. O. Gbadamosi7E. G. Adepoju8Obafemi Awolowo University, Ile-Ife, NigeriaObafemi Awolowo University, Ile-Ife, NigeriaObafemi Awolowo University, Ile-Ife, NigeriaInstitute of Public Health, Obafemi Awolowo University, Ile-Ife, NigeriaObafemi Awolowo University, Ile-Ife, NigeriaState Specialist Hospital, Osogbo, NigeriaState Specialist Hospital, Osogbo, NigeriaState Specialist Hospital, Osogbo, NigeriaState Specialist Hospital, Osogbo, Nigeria; Osun State University, Osogbo, NigeriaINTRODUCTION: Tuberculosis (TB) remains a major cause of death in people living with HIV/AIDS (PLWHA). This study assessed TB burden and its predictors among PLWHA receiving care at the State Specialist Hospital, Osogbo, Nigeria. METHODS: A prospective study was conducted among PLWHA screened clinically for TB from February 2009 till December 2019. Information collected included their socio-demographic characteristics, other variables, TB signs and symptoms, and CD4 count. PLWHA with at least one TB symptom or sign underwent laboratory diagnosis. Data were analyzed using descriptive and inferential statistics. RESULTS: A total of 4057 PLWHA were screened clinically for TB during the study period. They were 982 (24.2%) males and 3075 (75.8%) females. Six hundred and ninety-eight (33.4%) were diagnosed with TB. On logistic regression analysis, predictors of TB included being female (AOR=3.53, 95%CI=2.72-4.59, p<0.001), having lower education (AOR=2.53, 95%CI=2.07-3.10, p<0.001), having low socio-economic status (AOR=34.54, 95%CI=21.10-56.52, p=0.0001), being underweight (AOR=3.28, 95%CI=2.69-4.10, p<0.001) and having CD4 count <200/ml (AOR=3.69, 95%CI=3.04-4.47, p<0.001). CONCLUSION: PLWHA had a high TB burden with predictors including low socio-economic status, being female, having had lower education, low CD4 count, and being underweight. Addressing these factors may reduce the TB burden among PLWHA.tuberculosistb burdenpredictorsplwhahiv/aids |
| spellingShingle | S. A. Olowookere O. F. Awopeju F. O. Fehintola O. Arije T. O. Ojo O. I. Obe-Adeoye O. A. Aina M. O. Gbadamosi E. G. Adepoju Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study Rwanda Medical Journal tuberculosis tb burden predictors plwha hiv/aids |
| title | Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study |
| title_full | Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study |
| title_fullStr | Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study |
| title_full_unstemmed | Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study |
| title_short | Tuberculosis burden and its predictors among people living with HIV/AIDS at a Nigerian treatment centre: a prospective study |
| title_sort | tuberculosis burden and its predictors among people living with hiv aids at a nigerian treatment centre a prospective study |
| topic | tuberculosis tb burden predictors plwha hiv/aids |
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