An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise
Nanotechnology has widespread applications in sports; however, there are very few studies reporting the use of nanotechnology to enhance physical performance. We hypothesize that a natural-mineral-based novel nanomaterial, which was developed from Japanese hot springs, might overcome the limitations...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/6/980 |
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| author | Tomohiro Akiyama Shinnosuke Hatakeyama Kazuhisa Kawamoto Hideko Nihei Takamichi Hirata Tomohiro Nomura |
| author_facet | Tomohiro Akiyama Shinnosuke Hatakeyama Kazuhisa Kawamoto Hideko Nihei Takamichi Hirata Tomohiro Nomura |
| author_sort | Tomohiro Akiyama |
| collection | DOAJ |
| description | Nanotechnology has widespread applications in sports; however, there are very few studies reporting the use of nanotechnology to enhance physical performance. We hypothesize that a natural-mineral-based novel nanomaterial, which was developed from Japanese hot springs, might overcome the limitations. We examined if it could enhance physical performance. We conducted a treadmill exercise test on 18 students of athletic clubs at Fukushima University, Japan, and measured heart rate, oxygen consumption, maximal oxygen consumption, CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> production, and respiratory quotient 106 times in total. The results showed that the elevation of heart rate was significantly suppressed in the natural-mineral-based nanomaterial group, while no differences were observed in oxygen consumption, maximal oxygen consumption, CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> production, and respiratory quotient between groups. To our knowledge, this result is the first evidence where an improvement of cardiovascular and pulmonary functions was induced by bringing a natural-mineral-based nanomaterial into contact with or close to a living body without pharmacological intervention or physical intervention. This could open new avenue of biomedical industries even in an eco-friendly direction. The precise mechanisms remain a matter for further investigation; however, we may assume that endothelial NO synthase, hemoglobin and endothelium-derived hyperpolarizing factor are deeply involved in the improvement of cardiovascular and pulmonary functions. |
| first_indexed | 2024-03-09T13:07:46Z |
| format | Article |
| id | doaj.art-86ac42f89f534920964a07f1e30fe360 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T13:07:46Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-86ac42f89f534920964a07f1e30fe3602023-11-30T21:46:29ZengMDPI AGNanomaterials2079-49912022-03-0112698010.3390/nano12060980An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic ExerciseTomohiro Akiyama0Shinnosuke Hatakeyama1Kazuhisa Kawamoto2Hideko Nihei3Takamichi Hirata4Tomohiro Nomura5Advanced Research Laboratories, Tokyo City University, Tokyo 158-0082, JapanGraduate School of Integrative Science and Engineering, Electrical Engineering and Chemistry, Tokyo City University, Tokyo 158-8557, JapanGraduate School of Human Development and Culture, Fukushima University, Fukushima 960-1296, JapanSports Division, Fukushima Prefecture, Fukushima 960-8065, JapanAdvanced Research Laboratories, Tokyo City University, Tokyo 158-0082, JapanOsaka City University, Osaka 558-8585, JapanNanotechnology has widespread applications in sports; however, there are very few studies reporting the use of nanotechnology to enhance physical performance. We hypothesize that a natural-mineral-based novel nanomaterial, which was developed from Japanese hot springs, might overcome the limitations. We examined if it could enhance physical performance. We conducted a treadmill exercise test on 18 students of athletic clubs at Fukushima University, Japan, and measured heart rate, oxygen consumption, maximal oxygen consumption, CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> production, and respiratory quotient 106 times in total. The results showed that the elevation of heart rate was significantly suppressed in the natural-mineral-based nanomaterial group, while no differences were observed in oxygen consumption, maximal oxygen consumption, CO<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> production, and respiratory quotient between groups. To our knowledge, this result is the first evidence where an improvement of cardiovascular and pulmonary functions was induced by bringing a natural-mineral-based nanomaterial into contact with or close to a living body without pharmacological intervention or physical intervention. This could open new avenue of biomedical industries even in an eco-friendly direction. The precise mechanisms remain a matter for further investigation; however, we may assume that endothelial NO synthase, hemoglobin and endothelium-derived hyperpolarizing factor are deeply involved in the improvement of cardiovascular and pulmonary functions.https://www.mdpi.com/2079-4991/12/6/980nanotechonologynatural-mineral-based novel nanomaterialnitric oxidehemoglobinheartratecardiopulmonary function improvement |
| spellingShingle | Tomohiro Akiyama Shinnosuke Hatakeyama Kazuhisa Kawamoto Hideko Nihei Takamichi Hirata Tomohiro Nomura An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise Nanomaterials nanotechonology natural-mineral-based novel nanomaterial nitric oxide hemoglobin heartrate cardiopulmonary function improvement |
| title | An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise |
| title_full | An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise |
| title_fullStr | An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise |
| title_full_unstemmed | An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise |
| title_short | An Externally-Applied, Natural-Mineral-Based Novel Nanomaterial IFMC Improves Cardiopulmonary Function under Aerobic Exercise |
| title_sort | externally applied natural mineral based novel nanomaterial ifmc improves cardiopulmonary function under aerobic exercise |
| topic | nanotechonology natural-mineral-based novel nanomaterial nitric oxide hemoglobin heartrate cardiopulmonary function improvement |
| url | https://www.mdpi.com/2079-4991/12/6/980 |
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