Multivariate effects of pH, salt, and Zn2+ ions on Aβ40 fibrillation

Several essential brain micro-environments like pH, salt, and metal ions play a vital role in modulating the amyloid-ß fibrillation, however, the cooperative modulation of these variables remains poorly understood. Here, the authors investigate multivariate effects of pH, ionic strength, and Zn2+ io...

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Bibliographic Details
Main Authors: Hongzhi Wang, Jinming Wu, Rebecca Sternke-Hoffmann, Wenwei Zheng, Cecilia Mörman, Jinghui Luo
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-022-00786-1

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