A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy
Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation. Attempts have been made to improve the success rate of lacrimal surgery by using different methods like using balloon catheters, lasers and antim...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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The Association of Otolaryngologists of India, West Bengal
2018-04-01
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| Series: | Bengal Journal of Otolaryngology and Head Neck Surgery |
| Subjects: | |
| Online Access: | https://bjohns.in/journal/index.php/bjohns/article/view/387 |
| _version_ | 1827334972260745216 |
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| author | Harikesh Sharma Ajay Mallick |
| author_facet | Harikesh Sharma Ajay Mallick |
| author_sort | Harikesh Sharma |
| collection | DOAJ |
| description | Introduction
Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation. Attempts have been made to improve the success rate of lacrimal surgery by using different methods like using balloon catheters, lasers and antimetabolites. This study aims to see change in success rate with and without the use of using Mitomycin-C in endonasal Dacryocystorhinostomy (DCR) surgery.
Materials and Methods
Sixty patients of acquired chronic dacryocystitis with nasolacrimal duct blockage, in the age group of 11-50 yrs were taken for study. Patients were alternatively divided into two groups A & B (30 patients in each group). Endoscopic dacryocystorhinostomy with Mitomycin-C application was performed in Group A and without Mitomycin-C application in Group B patients. Subjective assessment for symptomatic improvement and objective analysis obtained from results of syringing. The result data was subjected to Student’s t test and x2analysis.
Result
Age of patients varied from 11 to 50 yrs. The male to female ratio was 7:8 in group A while 2:3 in group B. The commonest age group was between 21 -30 years in both the groups. After 12 month follow up the success rate was 93% in both the groups. The results between the groups were found to be statistically not significant (p>0.05).
Conclusion
Mitomycin C was used in this study to assess its efficacy in improving the results of endoscopic DCR. Mitomycin C did not have significant effect on the outcomes of endoscopic DCR surgery for chronic dacryocystitis. |
| first_indexed | 2024-03-07T18:06:33Z |
| format | Article |
| id | doaj.art-86aede9bf9b34a508bdafc095177a7e0 |
| institution | Directory Open Access Journal |
| issn | 2395-2393 2395-2407 |
| language | English |
| last_indexed | 2024-03-07T18:06:33Z |
| publishDate | 2018-04-01 |
| publisher | The Association of Otolaryngologists of India, West Bengal |
| record_format | Article |
| series | Bengal Journal of Otolaryngology and Head Neck Surgery |
| spelling | doaj.art-86aede9bf9b34a508bdafc095177a7e02024-03-02T09:07:20ZengThe Association of Otolaryngologists of India, West BengalBengal Journal of Otolaryngology and Head Neck Surgery2395-23932395-24072018-04-012612934145A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic DacryocystorhinostomyHarikesh Sharma0Ajay Mallick1ARMY COLLEGE OF MEDICAL SCIENCES AND BASE HOSPITAL DELHI CANTT NEW DELHI-110010ARMY COLLEGE OF MEDICAL SCIENCES AND BASE HOSPITAL DELHI CANTT NEW DELHI-110010Introduction Common cause for failure of endonasal dacryocystorhinostomy is closure of the intranasal ostium usually due to granulation tissue formation. Attempts have been made to improve the success rate of lacrimal surgery by using different methods like using balloon catheters, lasers and antimetabolites. This study aims to see change in success rate with and without the use of using Mitomycin-C in endonasal Dacryocystorhinostomy (DCR) surgery. Materials and Methods Sixty patients of acquired chronic dacryocystitis with nasolacrimal duct blockage, in the age group of 11-50 yrs were taken for study. Patients were alternatively divided into two groups A & B (30 patients in each group). Endoscopic dacryocystorhinostomy with Mitomycin-C application was performed in Group A and without Mitomycin-C application in Group B patients. Subjective assessment for symptomatic improvement and objective analysis obtained from results of syringing. The result data was subjected to Student’s t test and x2analysis. Result Age of patients varied from 11 to 50 yrs. The male to female ratio was 7:8 in group A while 2:3 in group B. The commonest age group was between 21 -30 years in both the groups. After 12 month follow up the success rate was 93% in both the groups. The results between the groups were found to be statistically not significant (p>0.05). Conclusion Mitomycin C was used in this study to assess its efficacy in improving the results of endoscopic DCR. Mitomycin C did not have significant effect on the outcomes of endoscopic DCR surgery for chronic dacryocystitis.https://bjohns.in/journal/index.php/bjohns/article/view/387DacryocystitisDacryocystorhinostomyAntimetabolitesMitomycin |
| spellingShingle | Harikesh Sharma Ajay Mallick A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy Bengal Journal of Otolaryngology and Head Neck Surgery Dacryocystitis Dacryocystorhinostomy Antimetabolites Mitomycin |
| title | A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy |
| title_full | A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy |
| title_fullStr | A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy |
| title_full_unstemmed | A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy |
| title_short | A Study of Efficacy of Intraoperative Application of Mitomycin-C in Endoscopic Dacryocystorhinostomy |
| title_sort | study of efficacy of intraoperative application of mitomycin c in endoscopic dacryocystorhinostomy |
| topic | Dacryocystitis Dacryocystorhinostomy Antimetabolites Mitomycin |
| url | https://bjohns.in/journal/index.php/bjohns/article/view/387 |
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