Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction
Objectives: Left ventricular (LV) dysfunction heart failure is one of the causes of morbidity and mortality following ST elevation myocardial infarction (STEMI). This study was done to determine the clopidogrel effect in preventing reduced LV function in pa-tients with STEMI. Methods: In this study,...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2010-01-01
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| Series: | International Journal of Preventive Medicine |
| Subjects: | |
| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2010;volume=1;issue=4;spage=257;epage=259;aulast=Khosravi |
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| author | Pejman Khosravi Hasan Shemirani Behnoud Hedayatpour Allahyar Golabchi |
| author_facet | Pejman Khosravi Hasan Shemirani Behnoud Hedayatpour Allahyar Golabchi |
| author_sort | Pejman Khosravi |
| collection | DOAJ |
| description | Objectives: Left ventricular (LV) dysfunction heart failure is one of the causes of morbidity and mortality following ST elevation myocardial infarction (STEMI). This study was done to determine the clopidogrel effect in preventing reduced LV function in pa-tients with STEMI.
Methods: In this study, 144 patients with STEMI admitted to the Isfahan University of Medical Sciences hospitals were followed in two groups for one month. The case group received Clopidogrel, 300 mg, on admission and then, 75 mg daily, while the control group received routine therapy for STEMI without Clopidogrel. Left ventricular ejection fraction (LVEF) on the 4 th day and one month after STEMI was measured by echocardiography. The re-sults of LVEF were compared within and between groups.
Results: The mean LVEF in the case group on the 4 th day and one month after STEMI were 45.92 and 52.15%, respectively (P<0.001). The mean LVEF in the control group on 4 th day and one month after STEMI were 44.72 and 42.71%, respectively.
Conclusions: We suggest that Clopidogrel is effective in preven-tion of LVEF reduction in patients with STEMI. |
| first_indexed | 2024-12-23T20:53:01Z |
| format | Article |
| id | doaj.art-86b82450638848b5b0b42d14d6d37246 |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-12-23T20:53:01Z |
| publishDate | 2010-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-86b82450638848b5b0b42d14d6d372462022-12-21T17:31:36ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132010-01-0114257259Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarctionPejman KhosraviHasan ShemiraniBehnoud HedayatpourAllahyar GolabchiObjectives: Left ventricular (LV) dysfunction heart failure is one of the causes of morbidity and mortality following ST elevation myocardial infarction (STEMI). This study was done to determine the clopidogrel effect in preventing reduced LV function in pa-tients with STEMI. Methods: In this study, 144 patients with STEMI admitted to the Isfahan University of Medical Sciences hospitals were followed in two groups for one month. The case group received Clopidogrel, 300 mg, on admission and then, 75 mg daily, while the control group received routine therapy for STEMI without Clopidogrel. Left ventricular ejection fraction (LVEF) on the 4 th day and one month after STEMI was measured by echocardiography. The re-sults of LVEF were compared within and between groups. Results: The mean LVEF in the case group on the 4 th day and one month after STEMI were 45.92 and 52.15%, respectively (P<0.001). The mean LVEF in the control group on 4 th day and one month after STEMI were 44.72 and 42.71%, respectively. Conclusions: We suggest that Clopidogrel is effective in preven-tion of LVEF reduction in patients with STEMI.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2010;volume=1;issue=4;spage=257;epage=259;aulast=KhosraviHeart failure; Myocardial infarction; Prevention |
| spellingShingle | Pejman Khosravi Hasan Shemirani Behnoud Hedayatpour Allahyar Golabchi Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction International Journal of Preventive Medicine Heart failure; Myocardial infarction; Prevention |
| title | Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| title_full | Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| title_fullStr | Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| title_full_unstemmed | Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| title_short | Assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| title_sort | assessment of clopidogrel on the left ventricular ejection fraction in acute myocardial infarction |
| topic | Heart failure; Myocardial infarction; Prevention |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2010;volume=1;issue=4;spage=257;epage=259;aulast=Khosravi |
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