Proteasomal subunit depletions differentially affect germline integrity in C. elegans

Proteasomal subunit depletions differentially affect germline integrity in C. elegans

The 26S proteasome is a multi-subunit protein complex that is canonically known for its ability to degrade proteins in cells and maintain protein homeostasis. Non-canonical or non-proteolytic roles of proteasomal subunits exist but remain less well studied. We provide characterization of germline-sp...

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Bibliographic Details
Main Authors: Lourds Michelle Fernando, Cristina Quesada-Candela, Makaelah Murray, Caroline Ugoaru, Judith L. Yanowitz, Anna K. Allen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
C. elegans
germ line
19S regulatory particle
proteasome
meiosis
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.901320/full

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