Staphylococcus aureus activates the NLRP3 inflammasome in human and rat conjunctival goblet cells.

Staphylococcus aureus activates the NLRP3 inflammasome in human and rat conjunctival goblet cells.

The conjunctiva is a moist mucosal membrane that is constantly exposed to an array of potential pathogens and triggers of inflammation. The NACHT, leucine rich repeat (LRR), and pyrin domain-containing protein 3 (NLRP3) is a Nod-like receptor that can sense pathogens or other triggers, and is highly...

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Bibliographic Details
Main Authors: Victoria E McGilligan, Meredith S Gregory-Ksander, Dayu Li, Jonathan E Moore, Robin R Hodges, Michael S Gilmore, Tara C B Moore, Darlene A Dartt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3769353?pdf=render

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