Speed of development and speed of progression of primary open-angle glaucoma
Purpose: To perform the analysis of the results of primary open-angle glaucoma (POAG) patients’ examination at presentation and to build objective criteria for the development and progression of the disease. Materials and Methods: One hundred and seventy two patients (344 eyes) diagnosed with POA...
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Format: | Article |
Language: | English |
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Ukrainian Society of Ophthalmologists
2018-10-01
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Series: | Journal of Ophthalmology |
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Online Access: | https://www.ozhurnal.com/en/archive/2018/5/3-fulltext |
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author | S.O. Rykov A.V. Burdei O.V. Petrenko S.Yu. Mogilevskyy L.I. Denisyuk |
author_facet | S.O. Rykov A.V. Burdei O.V. Petrenko S.Yu. Mogilevskyy L.I. Denisyuk |
author_sort | S.O. Rykov |
collection | DOAJ |
description | Purpose: To perform the analysis of the results of primary open-angle glaucoma (POAG) patients’ examination at presentation and to build objective criteria for the development and progression of the disease.
Materials and Methods: One hundred and seventy two patients (344 eyes) diagnosed with POAG were involved into the study. In addition, the control group comprised 98 volunteers (196 eyes) diagnosed with no POAG. The age at presentation ranged from 40 to 74 years with a mean of 57.3±1.1 years. Statistical analyses were performed using MedStat and MedCalc v.15.1 (MedCalc Software bvba).
Results: Disease duration was found to increase from 0 to 3 years with an increase in the stage of POAG (Н=10869; p=0.00Е-01). Both absolute IOP values and IOP categories progressively increased with an increase in the stage of POAG (Н=88.76, р=0.00Е-01 and Н=90.13, р=0.00Е-01, respectively). Two indices, SDPOAG (speed of POAG development, expressed as stage/life year), and SPPOAG (speed of POAG progression, expressed as stage/disease year), were proposed as measures for assessing speed of the pathological process. These were found to progressively increase with an increase in the stage of the pathological process (р<0.05). The effect of SPPOAG on the stage of POAG was found to be statistically significant (F=21.1; p=2.16E-11). |
first_indexed | 2024-03-08T19:22:32Z |
format | Article |
id | doaj.art-86c3aff498644651ab93e0a1be54205a |
institution | Directory Open Access Journal |
issn | 2412-8740 |
language | English |
last_indexed | 2024-03-08T19:22:32Z |
publishDate | 2018-10-01 |
publisher | Ukrainian Society of Ophthalmologists |
record_format | Article |
series | Journal of Ophthalmology |
spelling | doaj.art-86c3aff498644651ab93e0a1be54205a2023-12-26T14:22:31ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402018-10-015202510.31288/oftalmolzh201852025Speed of development and speed of progression of primary open-angle glaucomaS.O. Rykov0A.V. Burdei1O.V. Petrenko2S.Yu. Mogilevskyy3L.I. Denisyuk4Shupik National Medical Academy of Postgraduate EducationShupik National Medical Academy of Postgraduate EducationShupik National Medical Academy of Postgraduate EducationShupik National Medical Academy of Postgraduate EducationShupik National Medical Academy of Postgraduate EducationPurpose: To perform the analysis of the results of primary open-angle glaucoma (POAG) patients’ examination at presentation and to build objective criteria for the development and progression of the disease. Materials and Methods: One hundred and seventy two patients (344 eyes) diagnosed with POAG were involved into the study. In addition, the control group comprised 98 volunteers (196 eyes) diagnosed with no POAG. The age at presentation ranged from 40 to 74 years with a mean of 57.3±1.1 years. Statistical analyses were performed using MedStat and MedCalc v.15.1 (MedCalc Software bvba). Results: Disease duration was found to increase from 0 to 3 years with an increase in the stage of POAG (Н=10869; p=0.00Е-01). Both absolute IOP values and IOP categories progressively increased with an increase in the stage of POAG (Н=88.76, р=0.00Е-01 and Н=90.13, р=0.00Е-01, respectively). Two indices, SDPOAG (speed of POAG development, expressed as stage/life year), and SPPOAG (speed of POAG progression, expressed as stage/disease year), were proposed as measures for assessing speed of the pathological process. These were found to progressively increase with an increase in the stage of the pathological process (р<0.05). The effect of SPPOAG on the stage of POAG was found to be statistically significant (F=21.1; p=2.16E-11).https://www.ozhurnal.com/en/archive/2018/5/3-fulltextprimary open-angle glaucomaspeed of poag developmentspeed of poag progression |
spellingShingle | S.O. Rykov A.V. Burdei O.V. Petrenko S.Yu. Mogilevskyy L.I. Denisyuk Speed of development and speed of progression of primary open-angle glaucoma Journal of Ophthalmology primary open-angle glaucoma speed of poag development speed of poag progression |
title | Speed of development and speed of progression of primary open-angle glaucoma |
title_full | Speed of development and speed of progression of primary open-angle glaucoma |
title_fullStr | Speed of development and speed of progression of primary open-angle glaucoma |
title_full_unstemmed | Speed of development and speed of progression of primary open-angle glaucoma |
title_short | Speed of development and speed of progression of primary open-angle glaucoma |
title_sort | speed of development and speed of progression of primary open angle glaucoma |
topic | primary open-angle glaucoma speed of poag development speed of poag progression |
url | https://www.ozhurnal.com/en/archive/2018/5/3-fulltext |
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