Differences in SpeB protease activity among group A streptococci associated with superficial, invasive, and autoimmune disease.
The secreted cysteine proteinase SpeB is an important virulence factor of group A streptococci (GAS), whereby SpeB activity varies widely among strains. To establish the degree to which SpeB activity correlates with disease, GAS organisms were recovered from patients with pharyngitis, impetigo, inva...
Main Authors: | Anhphan T Ly, John P Noto, Odaelys L Walwyn, Robert R Tanz, Stanford T Shulman, William Kabat, Debra E Bessen |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC5435240?pdf=render |
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