Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment

Background : A retrospective study was done in the Pediatric ward /AL-Kadhimiyia Teaching Hospital on cases diagnosed as idiopathic thrombocytopenic Purpura admitted since the first of January1992 – the end of December 2004. Aim of the study : The objective of this paper is to review the natural his...

Full description

Bibliographic Details
Main Author: Sawsan S. Abbas
Format: Article
Language:English
Published: College of Medicine University of Baghdad 2006-10-01
Series:مجلة كلية الطب
Subjects:
Online Access:http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1493
_version_ 1827393654064414720
author Sawsan S. Abbas
author_facet Sawsan S. Abbas
author_sort Sawsan S. Abbas
collection DOAJ
description Background : A retrospective study was done in the Pediatric ward /AL-Kadhimiyia Teaching Hospital on cases diagnosed as idiopathic thrombocytopenic Purpura admitted since the first of January1992 – the end of December 2004. Aim of the study : The objective of this paper is to review the natural history of idiopathic thrombocytopenic Purpura , presenting feature and response to treatment. Patients and methods : The review included age ,sex , clinical presentation , physical finding , complications , investigation ,treatment and course of the diseases . Results: total number of the patients were 65, peak age was between (2 -5) years, 40 cases (61.53%). Females were affected more than Males with male: female ratio of 1: 2.09 .There was no seasonal variation and all of the cases were preceded by viral upper respiratory tract infection .The main presentation was petechiae and ecchymosis, were found in all of them (100%) followed by epistaxis, 43 cases (66.15 %). In the majority the platelet count was < 20.000 X 10 9 /L, 32 cases (49.23 %) and the hemoglobin level was between 10 – 11gm /dl in most of them, 43 cases (66.15%). Steroid was the first line treatment, response occur within 2 – 3 weeks in the majority, 51 cases (78.46%). Chronic idiopathic thrombocytopenic Purpura occurred in 3 cases only (4.61%).Splenectomy was done in 2 of them (66.66%). No mortality detected. Conclusion : Idiopathic thrombocytopenic purpura is a mild disease with complete recovery in the majority of patients
first_indexed 2024-03-08T17:53:23Z
format Article
id doaj.art-86ce0d5cbc264ccca71dc66cb0714731
institution Directory Open Access Journal
issn 0041-9419
2410-8057
language English
last_indexed 2024-03-08T17:53:23Z
publishDate 2006-10-01
publisher College of Medicine University of Baghdad
record_format Article
series مجلة كلية الطب
spelling doaj.art-86ce0d5cbc264ccca71dc66cb07147312024-01-02T06:23:05ZengCollege of Medicine University of Baghdadمجلة كلية الطب0041-94192410-80572006-10-01483Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To TreatmentSawsan S. Abbas0Assistant Professor Department of Pediatrics College of Medicine AL-Nahraine UniversityBackground : A retrospective study was done in the Pediatric ward /AL-Kadhimiyia Teaching Hospital on cases diagnosed as idiopathic thrombocytopenic Purpura admitted since the first of January1992 – the end of December 2004. Aim of the study : The objective of this paper is to review the natural history of idiopathic thrombocytopenic Purpura , presenting feature and response to treatment. Patients and methods : The review included age ,sex , clinical presentation , physical finding , complications , investigation ,treatment and course of the diseases . Results: total number of the patients were 65, peak age was between (2 -5) years, 40 cases (61.53%). Females were affected more than Males with male: female ratio of 1: 2.09 .There was no seasonal variation and all of the cases were preceded by viral upper respiratory tract infection .The main presentation was petechiae and ecchymosis, were found in all of them (100%) followed by epistaxis, 43 cases (66.15 %). In the majority the platelet count was < 20.000 X 10 9 /L, 32 cases (49.23 %) and the hemoglobin level was between 10 – 11gm /dl in most of them, 43 cases (66.15%). Steroid was the first line treatment, response occur within 2 – 3 weeks in the majority, 51 cases (78.46%). Chronic idiopathic thrombocytopenic Purpura occurred in 3 cases only (4.61%).Splenectomy was done in 2 of them (66.66%). No mortality detected. Conclusion : Idiopathic thrombocytopenic purpura is a mild disease with complete recovery in the majority of patientshttp://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1493Thrombocytopenia, Purpura, Children
spellingShingle Sawsan S. Abbas
Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
مجلة كلية الطب
Thrombocytopenia, Purpura, Children
title Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
title_full Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
title_fullStr Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
title_full_unstemmed Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
title_short Childhood Idiopathic Thrombocytopenic Purpura: A Retrospective Analysis Of Clinical Features And Response To Treatment
title_sort childhood idiopathic thrombocytopenic purpura a retrospective analysis of clinical features and response to treatment
topic Thrombocytopenia, Purpura, Children
url http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/1493
work_keys_str_mv AT sawsansabbas childhoodidiopathicthrombocytopenicpurpuraaretrospectiveanalysisofclinicalfeaturesandresponsetotreatment