| Summary: | Skunk amdoparvovirus (<i>Carnivore amdoparvovirus 4</i>, SKAV) is closely related to Aleutian mink disease virus (AMDV) and circulates primarily in striped skunks (<i>Mephitis mephitis</i>) in North America. SKAV poses a threat to mustelid species due to reported isolated infections of captive American mink (<i>Neovison vison</i>) in British Columbia, Canada. We detected SKAV in a captive striped skunk in a German zoo by metagenomic sequencing. The pathological findings are dominated by lymphoplasmacellular inflammation and reveal similarities to its relative <i>Carnivore amdoparvovirus 1</i>, the causative agent of Aleutian mink disease. Phylogenetic analysis of the whole genome demonstrated 94.80% nucleotide sequence identity to a sequence from Ontario, Canada. This study is the first case description of a SKAV infection outside of North America.
|
|---|