Leishmaniasis with secondary hemophagocytic syndrome: a case report
Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fev...
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Format: | Article |
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Editorial Office of Journal of Diagnostics Concepts & Practice
2022-08-01
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Series: | Zhenduanxue lilun yu shijian |
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Online Access: | http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf |
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author | XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie |
author_facet | XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie |
author_sort | XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie |
collection | DOAJ |
description | Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fever of unknown origin, connective tissue disease” who was not effectively treated and was admitted to the Wuxi District Hospital in Jiangsu Province. After the analysis of clinical manifestations and the inquiry of the working history in the western mountain area, the patient was finally diagnosed as HPS secondary to Leishmaniasis by etiological and genetic examination. The patient was treated with antimony sodium gluconate for Leishmaniasis, according to the 1994 scheme of hemophagocytic syndrome treatment (HLH-94), and was discharged after his condition improved. When HPS secondary to Leishmaniasis, the disease develops rapidly. It is not common, and is easy to miss diagnosis. This paper reports a case of a patient in the eastern plain area, which the doctors should pay more attention to in clinic. |
first_indexed | 2024-04-11T04:38:05Z |
format | Article |
id | doaj.art-86cf99700cee4d58ad80290d71a18412 |
institution | Directory Open Access Journal |
issn | 1671-2870 |
language | zho |
last_indexed | 2024-04-11T04:38:05Z |
publishDate | 2022-08-01 |
publisher | Editorial Office of Journal of Diagnostics Concepts & Practice |
record_format | Article |
series | Zhenduanxue lilun yu shijian |
spelling | doaj.art-86cf99700cee4d58ad80290d71a184122022-12-28T08:51:23ZzhoEditorial Office of Journal of Diagnostics Concepts & PracticeZhenduanxue lilun yu shijian1671-28702022-08-01210452452610.16150/j.1671-2870.2022.04.018Leishmaniasis with secondary hemophagocytic syndrome: a case reportXIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie01. Department of Laboratory, Wuxi Branch, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Jiangsu, Wuxi 214000, China;2. Department of Laboratory, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaLeishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fever of unknown origin, connective tissue disease” who was not effectively treated and was admitted to the Wuxi District Hospital in Jiangsu Province. After the analysis of clinical manifestations and the inquiry of the working history in the western mountain area, the patient was finally diagnosed as HPS secondary to Leishmaniasis by etiological and genetic examination. The patient was treated with antimony sodium gluconate for Leishmaniasis, according to the 1994 scheme of hemophagocytic syndrome treatment (HLH-94), and was discharged after his condition improved. When HPS secondary to Leishmaniasis, the disease develops rapidly. It is not common, and is easy to miss diagnosis. This paper reports a case of a patient in the eastern plain area, which the doctors should pay more attention to in clinic.http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf|leishmaniasis|hemophagocytic syndrome|fever |
spellingShingle | XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie Leishmaniasis with secondary hemophagocytic syndrome: a case report Zhenduanxue lilun yu shijian |leishmaniasis|hemophagocytic syndrome|fever |
title | Leishmaniasis with secondary hemophagocytic syndrome: a case report |
title_full | Leishmaniasis with secondary hemophagocytic syndrome: a case report |
title_fullStr | Leishmaniasis with secondary hemophagocytic syndrome: a case report |
title_full_unstemmed | Leishmaniasis with secondary hemophagocytic syndrome: a case report |
title_short | Leishmaniasis with secondary hemophagocytic syndrome: a case report |
title_sort | leishmaniasis with secondary hemophagocytic syndrome a case report |
topic | |leishmaniasis|hemophagocytic syndrome|fever |
url | http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf |
work_keys_str_mv | AT xiongxinhailijiadingxiaosongjicongcongshihourongxiangminjie leishmaniasiswithsecondaryhemophagocyticsyndromeacasereport |