Leishmaniasis with secondary hemophagocytic syndrome: a case report

Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fev...

Full description

Bibliographic Details
Main Author: XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
Format: Article
Language:zho
Published: Editorial Office of Journal of Diagnostics Concepts & Practice 2022-08-01
Series:Zhenduanxue lilun yu shijian
Subjects:
Online Access:http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf
_version_ 1828085309760339968
author XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
author_facet XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
author_sort XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
collection DOAJ
description Leishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fever of unknown origin, connective tissue disease” who was not effectively treated and was admitted to the Wuxi District Hospital in Jiangsu Province. After the analysis of clinical manifestations and the inquiry of the working history in the western mountain area, the patient was finally diagnosed as HPS secondary to Leishmaniasis by etiological and genetic examination. The patient was treated with antimony sodium gluconate for Leishmaniasis, according to the 1994 scheme of hemophagocytic syndrome treatment (HLH-94), and was discharged after his condition improved. When HPS secondary to Leishmaniasis, the disease develops rapidly. It is not common, and is easy to miss diagnosis. This paper reports a case of a patient in the eastern plain area, which the doctors should pay more attention to in clinic.
first_indexed 2024-04-11T04:38:05Z
format Article
id doaj.art-86cf99700cee4d58ad80290d71a18412
institution Directory Open Access Journal
issn 1671-2870
language zho
last_indexed 2024-04-11T04:38:05Z
publishDate 2022-08-01
publisher Editorial Office of Journal of Diagnostics Concepts & Practice
record_format Article
series Zhenduanxue lilun yu shijian
spelling doaj.art-86cf99700cee4d58ad80290d71a184122022-12-28T08:51:23ZzhoEditorial Office of Journal of Diagnostics Concepts & PracticeZhenduanxue lilun yu shijian1671-28702022-08-01210452452610.16150/j.1671-2870.2022.04.018Leishmaniasis with secondary hemophagocytic syndrome: a case reportXIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie01. Department of Laboratory, Wuxi Branch, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Jiangsu, Wuxi 214000, China;2. Department of Laboratory, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaLeishmaniasis is an infection caused by Leishmania. Different species of Leishmania cause different clinical syndromes. Hemophagocytic syndrome (HPS) is an immune related systemic inflammatory response syndrome mediated by many factors. This paper reported that one male patient with “fever of unknown origin, connective tissue disease” who was not effectively treated and was admitted to the Wuxi District Hospital in Jiangsu Province. After the analysis of clinical manifestations and the inquiry of the working history in the western mountain area, the patient was finally diagnosed as HPS secondary to Leishmaniasis by etiological and genetic examination. The patient was treated with antimony sodium gluconate for Leishmaniasis, according to the 1994 scheme of hemophagocytic syndrome treatment (HLH-94), and was discharged after his condition improved. When HPS secondary to Leishmaniasis, the disease develops rapidly. It is not common, and is easy to miss diagnosis. This paper reports a case of a patient in the eastern plain area, which the doctors should pay more attention to in clinic.http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf|leishmaniasis|hemophagocytic syndrome|fever
spellingShingle XIONG Xinhai, LI Jia, DING Xiaosong, JI Congcong, SHI Hourong, XIANG Minjie
Leishmaniasis with secondary hemophagocytic syndrome: a case report
Zhenduanxue lilun yu shijian
|leishmaniasis|hemophagocytic syndrome|fever
title Leishmaniasis with secondary hemophagocytic syndrome: a case report
title_full Leishmaniasis with secondary hemophagocytic syndrome: a case report
title_fullStr Leishmaniasis with secondary hemophagocytic syndrome: a case report
title_full_unstemmed Leishmaniasis with secondary hemophagocytic syndrome: a case report
title_short Leishmaniasis with secondary hemophagocytic syndrome: a case report
title_sort leishmaniasis with secondary hemophagocytic syndrome a case report
topic |leishmaniasis|hemophagocytic syndrome|fever
url http://www.qk.sjtu.edu.cn/jdcp/fileup/1671-2870/PDF/1667814420653-1041176979.pdf
work_keys_str_mv AT xiongxinhailijiadingxiaosongjicongcongshihourongxiangminjie leishmaniasiswithsecondaryhemophagocyticsyndromeacasereport