Diagnostic Accuracy of Droplet Digital PCR and Amplification Refractory Mutation System PCR for Detecting EGFR Mutation in Cell-Free DNA of Lung Cancer: A Meta-Analysis

Diagnostic Accuracy of Droplet Digital PCR and Amplification Refractory Mutation System PCR for Detecting EGFR Mutation in Cell-Free DNA of Lung Cancer: A Meta-Analysis

Background: Epidermal growth factor receptor (EGFR) mutation testing in plasma cell-free DNA (cfDNA) from advanced lung cancer patients is an emerging clinical tool. This meta-analysis was designed to determine the diagnostic accuracy of two common PCR systems, droplet digital PCR (ddPCR) and amplif...

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Bibliographic Details
Main Authors: Caichen Li, Qihua He, Hengrui Liang, Bo Cheng, Jianfu Li, Shan Xiong, Yi Zhao, Minzhang Guo, Zhichao Liu, Jianxing He, Wenhua Liang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Oncology
Subjects:
lung cancer
droplet digital PCR (ddPCR)
amplification refractory mutation system PCR (ARMS-PCR)
cell free DNA (cfDNA)
epidermal growth factor receptor (EGFR)
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00290/full

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