Avian Neuropeptide Y: Beyond Feed Intake Regulation
Neuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian spec...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-04-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/9/4/171 |
| _version_ | 1797443231901810688 |
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| author | Elizabeth S. Greene Nedra Abdelli Jalila S. Dridi Sami Dridi |
| author_facet | Elizabeth S. Greene Nedra Abdelli Jalila S. Dridi Sami Dridi |
| author_sort | Elizabeth S. Greene |
| collection | DOAJ |
| description | Neuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian species. Indeed, NPY has been shown to be involved in the regulation of feed intake and energy homeostasis by exerting stimulatory effects on appetite and feeding behavior in several species including chickens, rabbits, rats and mouse. More recent studies have shown that this neuropeptide and its receptors are expressed in various peripheral tissues, including the thyroid, heart, spleen, adrenal glands, white adipose tissue, muscle and bone. Although well researched centrally, studies investigating the distribution and function of peripherally expressed NPY in avian (non-mammalian vertebrates) species are very limited. Thus, peripherally expressed NPY merits more consideration and further in-depth exploration to fully elucidate its functions, especially in non-mammalian species. The aim of the current review is to provide an integrated synopsis of both centrally and peripherally expressed NPY, with a special focus on the distribution and function of the latter. |
| first_indexed | 2024-03-09T12:54:00Z |
| format | Article |
| id | doaj.art-86d08e4fc8864e3ea9840cdafa03297c |
| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-09T12:54:00Z |
| publishDate | 2022-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-86d08e4fc8864e3ea9840cdafa03297c2023-11-30T22:02:59ZengMDPI AGVeterinary Sciences2306-73812022-04-019417110.3390/vetsci9040171Avian Neuropeptide Y: Beyond Feed Intake RegulationElizabeth S. Greene0Nedra Abdelli1Jalila S. Dridi2Sami Dridi3Department of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USADepartment of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USAÉcole Universitaire de Kinésithérapie, Université d’Orléans, Rue de Chartres, 45100 Orleans, FranceDepartment of Poultry Science, University of Arkansas, Fayetteville, AR 72701, USANeuropeptide Y (NPY) is one of the most abundant and ubiquitously expressed neuropeptides in both the central and peripheral nervous systems, and its regulatory effects on feed intake and appetite- have been extensively studied in a wide variety of animals, including mammalian and non-mammalian species. Indeed, NPY has been shown to be involved in the regulation of feed intake and energy homeostasis by exerting stimulatory effects on appetite and feeding behavior in several species including chickens, rabbits, rats and mouse. More recent studies have shown that this neuropeptide and its receptors are expressed in various peripheral tissues, including the thyroid, heart, spleen, adrenal glands, white adipose tissue, muscle and bone. Although well researched centrally, studies investigating the distribution and function of peripherally expressed NPY in avian (non-mammalian vertebrates) species are very limited. Thus, peripherally expressed NPY merits more consideration and further in-depth exploration to fully elucidate its functions, especially in non-mammalian species. The aim of the current review is to provide an integrated synopsis of both centrally and peripherally expressed NPY, with a special focus on the distribution and function of the latter.https://www.mdpi.com/2306-7381/9/4/171neuropeptide Yfeed intake regulationadipose tissueliverimmune systemgut |
| spellingShingle | Elizabeth S. Greene Nedra Abdelli Jalila S. Dridi Sami Dridi Avian Neuropeptide Y: Beyond Feed Intake Regulation Veterinary Sciences neuropeptide Y feed intake regulation adipose tissue liver immune system gut |
| title | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
| title_full | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
| title_fullStr | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
| title_full_unstemmed | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
| title_short | Avian Neuropeptide Y: Beyond Feed Intake Regulation |
| title_sort | avian neuropeptide y beyond feed intake regulation |
| topic | neuropeptide Y feed intake regulation adipose tissue liver immune system gut |
| url | https://www.mdpi.com/2306-7381/9/4/171 |
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