Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina

In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy...

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Bibliographic Details
Main Authors: Yu. N. Fedulaev, I. M. Korochkin
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-06-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2152
Description
Summary:In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy was associated with: nitroglycerine dose reduction; physical stress tolerance increase; decrease of qualitative and quantitative signs of pain and painless myocardial ischemia, supraventricular and ventricular extrasystoles, QC dispersion; increase in timely and spectral parameters of heart rate variability.
ISSN:1560-4071
2618-7620