Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina

In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy...

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Main Authors: Yu. N. Fedulaev, I. M. Korochkin
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2007-06-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/2152
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author Yu. N. Fedulaev
I. M. Korochkin
author_facet Yu. N. Fedulaev
I. M. Korochkin
author_sort Yu. N. Fedulaev
collection DOAJ
description In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy was associated with: nitroglycerine dose reduction; physical stress tolerance increase; decrease of qualitative and quantitative signs of pain and painless myocardial ischemia, supraventricular and ventricular extrasystoles, QC dispersion; increase in timely and spectral parameters of heart rate variability.
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spelling doaj.art-86d0ac014e86429c9f12c29bf207b9f32025-03-02T11:42:23Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-06-010356611904Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort anginaYu. N. Fedulaev0I. M. Korochkin1Российский государственный медицинский университетРоссийский государственный медицинский университетIn total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy was associated with: nitroglycerine dose reduction; physical stress tolerance increase; decrease of qualitative and quantitative signs of pain and painless myocardial ischemia, supraventricular and ventricular extrasystoles, QC dispersion; increase in timely and spectral parameters of heart rate variability.https://russjcardiol.elpub.ru/jour/article/view/2152стенокардия напряжения, триметазид, критерии эффективности
spellingShingle Yu. N. Fedulaev
I. M. Korochkin
Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
Российский кардиологический журнал
стенокардия напряжения, триметазид, критерии эффективности
title Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
title_full Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
title_fullStr Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
title_full_unstemmed Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
title_short Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
title_sort clinical and electrocardiographic markers of trimetazide effectiveness in patients with functional class ii iii effort angina
topic стенокардия напряжения, триметазид, критерии эффективности
url https://russjcardiol.elpub.ru/jour/article/view/2152
work_keys_str_mv AT yunfedulaev clinicalandelectrocardiographicmarkersoftrimetazideeffectivenessinpatientswithfunctionalclassiiiiieffortangina
AT imkorochkin clinicalandelectrocardiographicmarkersoftrimetazideeffectivenessinpatientswithfunctionalclassiiiiieffortangina