Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina
In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy...
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Format: | Article |
Language: | Russian |
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«FIRMA «SILICEA» LLC
2007-06-01
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Series: | Российский кардиологический журнал |
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2152 |
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author | Yu. N. Fedulaev I. M. Korochkin |
author_facet | Yu. N. Fedulaev I. M. Korochkin |
author_sort | Yu. N. Fedulaev |
collection | DOAJ |
description | In total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy was associated with: nitroglycerine dose reduction; physical stress tolerance increase; decrease of qualitative and quantitative signs of pain and painless myocardial ischemia, supraventricular and ventricular extrasystoles, QC dispersion; increase in timely and spectral parameters of heart rate variability. |
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id | doaj.art-86d0ac014e86429c9f12c29bf207b9f3 |
institution | Directory Open Access Journal |
issn | 1560-4071 2618-7620 |
language | Russian |
last_indexed | 2025-03-14T09:34:19Z |
publishDate | 2007-06-01 |
publisher | «FIRMA «SILICEA» LLC |
record_format | Article |
series | Российский кардиологический журнал |
spelling | doaj.art-86d0ac014e86429c9f12c29bf207b9f32025-03-02T11:42:23Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202007-06-010356611904Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort anginaYu. N. Fedulaev0I. M. Korochkin1Российский государственный медицинский университетРоссийский государственный медицинский университетIn total, 156 patients with Functional Class (FC) II-III effort angina (EA) received standard therapy (beta-adrenoblockers, ACE inhibitors, disaggregants) plus trimetazide (60 mg/d) for 16 weeks. Control group included 40 patients with FC II-III EA, receiving standard therapy only. Combined therapy was associated with: nitroglycerine dose reduction; physical stress tolerance increase; decrease of qualitative and quantitative signs of pain and painless myocardial ischemia, supraventricular and ventricular extrasystoles, QC dispersion; increase in timely and spectral parameters of heart rate variability.https://russjcardiol.elpub.ru/jour/article/view/2152стенокардия напряжения, триметазид, критерии эффективности |
spellingShingle | Yu. N. Fedulaev I. M. Korochkin Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina Российский кардиологический журнал стенокардия напряжения, триметазид, критерии эффективности |
title | Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina |
title_full | Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina |
title_fullStr | Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina |
title_full_unstemmed | Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina |
title_short | Clinical and electrocardiographic markers of trimetazide effectiveness in patients with Functional Class II-III effort angina |
title_sort | clinical and electrocardiographic markers of trimetazide effectiveness in patients with functional class ii iii effort angina |
topic | стенокардия напряжения, триметазид, критерии эффективности |
url | https://russjcardiol.elpub.ru/jour/article/view/2152 |
work_keys_str_mv | AT yunfedulaev clinicalandelectrocardiographicmarkersoftrimetazideeffectivenessinpatientswithfunctionalclassiiiiieffortangina AT imkorochkin clinicalandelectrocardiographicmarkersoftrimetazideeffectivenessinpatientswithfunctionalclassiiiiieffortangina |