Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis
The cytosolic viral nucleic acid-sensing pathways converge on the protein kinase TANK-binding kinase 1 (TBK1) and the transcription factor interferon (IFN)-regulatory factor 3 (IRF3) to induce type I IFN production and antiviral immune responses. However, the mechanism that triggers the binding of T...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2023-01-01
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Series: | Journal of Innate Immunity |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/526324 |