Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome
(1) Background: Post-acute COVID-19 syndrome, characterized by persisting symptoms up to 12 weeks after the acute illness, impairs numerous people’s physical and mental health. (2) Methods: 64 inpatients and 79 outpatients, aged under 55 years, with post-acute COVID-19, were evaluated by a transthor...
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| Format: | Article |
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MDPI AG
2021-11-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/11/11/1456 |
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| author | Catalina Giurgi-Oncu Cristina Tudoran Gheorghe Nicusor Pop Cristina Bredicean Silvius Alexandru Pescariu Ana Giurgiuca Mariana Tudoran |
| author_facet | Catalina Giurgi-Oncu Cristina Tudoran Gheorghe Nicusor Pop Cristina Bredicean Silvius Alexandru Pescariu Ana Giurgiuca Mariana Tudoran |
| author_sort | Catalina Giurgi-Oncu |
| collection | DOAJ |
| description | (1) Background: Post-acute COVID-19 syndrome, characterized by persisting symptoms up to 12 weeks after the acute illness, impairs numerous people’s physical and mental health. (2) Methods: 64 inpatients and 79 outpatients, aged under 55 years, with post-acute COVID-19, were evaluated by a transthoracic echocardiography (TTE), mental health examination, Quality of Life (QoL) questionnaire, post-COVID-19 functional status scale (PCFS) and Hospital Anxiety and Depression Scale (HADS). (3) Results: all inpatients had mild/moderate pulmonary injury during acute COVID-19, in contrast to 37.97% of outpatients. Inpatients who reported an average of 5 persisting symptoms, had, predominantly, level 3 PCFS and a median QoL of 62, compared to outpatients, who reported an average of 3 symptoms, level 1 PCFS and a median QoL score of 70. Increased pulmonary artery pressure was detected in 28.11% of inpatients, compared to 17.72% of outpatients, while diastolic dysfunction was diagnosed in 28.12% of inpatients, in comparison with 20.25% of outpatients (<i>p</i> = 0.02). Abnormal systolic function was assessed in 9.37% of inpatients, and 7.58% of outpatients. According to the HADS depression subscale, 46.87% of inpatients and 27.84% of outpatients had clinical depression. Concomitantly, anxiety was detected in 34.37% of inpatients and 40.5% of outpatients (4) Conclusions: cardiovascular and mental health difficulties were frequently detected in patients with post-acute symptoms of COVID-19, which correlated with the number and intensity of persisting symptoms and reduced QoL scores. |
| first_indexed | 2024-03-10T05:39:27Z |
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| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T05:39:27Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-86d50f8c9b6c4d87a2c19bcb08af2e8c2023-11-22T22:37:57ZengMDPI AGBrain Sciences2076-34252021-11-011111145610.3390/brainsci11111456Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 SyndromeCatalina Giurgi-Oncu0Cristina Tudoran1Gheorghe Nicusor Pop2Cristina Bredicean3Silvius Alexandru Pescariu4Ana Giurgiuca5Mariana Tudoran6Department VIII Neurosciences, Discipline of Psychiatry, “Victor Babes” University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, Romania“Pius Brinzeu” County Emergency Hospital, 300723 Timisoara, RomaniaDepartment VI, Discipline of Cardiology, “Victor Babes” University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, RomaniaDepartment VIII Neurosciences, Discipline of Psychiatry, “Victor Babes” University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, RomaniaDepartment VI, Discipline of Cardiology, “Victor Babes” University of Medicine and Pharmacy Timisoara, No. 2 E. Murgu Square, 300041 Timisoara, RomaniaDepartment of Clinical Neuroscience, “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania“Pius Brinzeu” County Emergency Hospital, 300723 Timisoara, Romania(1) Background: Post-acute COVID-19 syndrome, characterized by persisting symptoms up to 12 weeks after the acute illness, impairs numerous people’s physical and mental health. (2) Methods: 64 inpatients and 79 outpatients, aged under 55 years, with post-acute COVID-19, were evaluated by a transthoracic echocardiography (TTE), mental health examination, Quality of Life (QoL) questionnaire, post-COVID-19 functional status scale (PCFS) and Hospital Anxiety and Depression Scale (HADS). (3) Results: all inpatients had mild/moderate pulmonary injury during acute COVID-19, in contrast to 37.97% of outpatients. Inpatients who reported an average of 5 persisting symptoms, had, predominantly, level 3 PCFS and a median QoL of 62, compared to outpatients, who reported an average of 3 symptoms, level 1 PCFS and a median QoL score of 70. Increased pulmonary artery pressure was detected in 28.11% of inpatients, compared to 17.72% of outpatients, while diastolic dysfunction was diagnosed in 28.12% of inpatients, in comparison with 20.25% of outpatients (<i>p</i> = 0.02). Abnormal systolic function was assessed in 9.37% of inpatients, and 7.58% of outpatients. According to the HADS depression subscale, 46.87% of inpatients and 27.84% of outpatients had clinical depression. Concomitantly, anxiety was detected in 34.37% of inpatients and 40.5% of outpatients (4) Conclusions: cardiovascular and mental health difficulties were frequently detected in patients with post-acute symptoms of COVID-19, which correlated with the number and intensity of persisting symptoms and reduced QoL scores.https://www.mdpi.com/2076-3425/11/11/1456post-acute COVID-19mental illnessanxietydepressioncardiovascular complicationsquality of life |
| spellingShingle | Catalina Giurgi-Oncu Cristina Tudoran Gheorghe Nicusor Pop Cristina Bredicean Silvius Alexandru Pescariu Ana Giurgiuca Mariana Tudoran Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome Brain Sciences post-acute COVID-19 mental illness anxiety depression cardiovascular complications quality of life |
| title | Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome |
| title_full | Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome |
| title_fullStr | Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome |
| title_full_unstemmed | Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome |
| title_short | Cardiovascular Abnormalities and Mental Health Difficulties Result in a Reduced Quality of Life in the Post-Acute COVID-19 Syndrome |
| title_sort | cardiovascular abnormalities and mental health difficulties result in a reduced quality of life in the post acute covid 19 syndrome |
| topic | post-acute COVID-19 mental illness anxiety depression cardiovascular complications quality of life |
| url | https://www.mdpi.com/2076-3425/11/11/1456 |
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