Prognostic Significance of MGMT Promoter Methylation in Egyptian GBM Patients: A Single-institution Experience

Prognostic Significance of MGMT Promoter Methylation in Egyptian GBM Patients: A Single-institution Experience

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Background: Glioblastoma Multiforme (GBM) is the highest-mortality tumor of the central nervous system. Epigenetic silencing of the MGMT gene by promoter methylation is associated with loss of MGMT expression and deficiency in MGMT-mediated DNA repair, which is affiliated with improved survival in p...

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Bibliographic Details
Main Authors:	Rabab Abdel Moneim, Mohamed Abdel-Rafei, Hesham Hassan, Ibrahim El-Zawahry, Wedad Bassam Hashem
Format:	Article
Language:	English
Published:	West Asia Organization for Cancer Prevention 2018-02-01
Series:	Asian Pacific Journal of Cancer Biology
Subjects:	gbm- epigenetic silencing- un-methylation- overall survival
Online Access:	http://www.waocp.com/journal/index.php/apjcb/article/view/227

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