Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy

Targeting delivery of simvastatin using ICAM-1 antibody-conjugated nanostructured lipid carriers for acute lung injury therapy

Acute lung injury (ALI) is a critical illness without effective therapeutic modalities currently. Recent studies indicated potential efficacy of statins for ALI, while high-dose statins was suggested to be significant for attenuating inflammation in vivo. Therefore, a lung-targeted drug delivery sys...

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Bibliographic Details
Main Authors:	Shu-Juan Li, Xiao-Juan Wang, Jing-Bo Hu, Xu-Qi Kang, Li Chen, Xiao-Ling Xu, Xiao-Ying Ying, Sai-Ping Jiang, Yong-Zhong Du
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-01-01
Series:	Drug Delivery
Subjects:	lung targeting nanostructured lipid carriers icam-1 simvastatin delivery acute lung injury
Online Access:	http://dx.doi.org/10.1080/10717544.2016.1259369

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