High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission
For three cohorts (the elderly, socially deprived, and those with chronic disabling disease), the relationship between the concentrations of particulate matter (PM10), sulphur dioxide (SO2), or oxides of nitrogen (NOx) at the time of hospital admission and outcomes (30-day in-hospital mortality) wer...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-10-01
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| Series: | Toxics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2305-6304/5/4/27 |
| _version_ | 1818136477474750464 |
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| author | Seán Cournane Richard Conway Declan Byrne Deirdre O’Riordan Seamus Coveney Bernard Silke |
| author_facet | Seán Cournane Richard Conway Declan Byrne Deirdre O’Riordan Seamus Coveney Bernard Silke |
| author_sort | Seán Cournane |
| collection | DOAJ |
| description | For three cohorts (the elderly, socially deprived, and those with chronic disabling disease), the relationship between the concentrations of particulate matter (PM10), sulphur dioxide (SO2), or oxides of nitrogen (NOx) at the time of hospital admission and outcomes (30-day in-hospital mortality) were investigated All emergency admissions (90,423 episodes, recorded in 48,035 patients) between 2002 and 2015 were examined. PM10, SO2, and NOx daily levels from the hospital catchment area were correlated with the outcomes for the older admission cohort (>70 years), those of lower socio-economic status (SES), and with more disabling disease. Adjusted for acuity and complexity, the level of each pollutant on the day of admission independently predicted the 30-day mortality: for PM10–OR 1.11 (95% CI: 1.08, 1.15), SO2–1.20 (95% CI: 1.16, 1.24), and NOx–1.09 (1.06–1.13). For the older admission cohort (≥70 years), as admission day pollution increased (NOx quintiles) the 30-day mortality was higher in the elderly (14.2% vs. 11.3%: p < 0.001). Persons with a lower SES were at increased risk. Persons with more disabling disease also had worse outcomes on days with higher admission particulate matter (PM10 quintiles). Levels of pollutants on the day of admission of emergency medical admissions predicted 30-day hospital mortality. |
| first_indexed | 2024-12-11T09:41:02Z |
| format | Article |
| id | doaj.art-86df28b8da0d4df7b1959761ea7775f0 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-12-11T09:41:02Z |
| publishDate | 2017-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-86df28b8da0d4df7b1959761ea7775f02022-12-22T01:12:40ZengMDPI AGToxics2305-63042017-10-01542710.3390/toxics5040027toxics5040027High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical AdmissionSeán Cournane0Richard Conway1Declan Byrne2Deirdre O’Riordan3Seamus Coveney4Bernard Silke5Medical Physics Department, St James’s Hospital (SJH), 8 Dublin, IrelandDepartment of Internal Medicine, St James’s Hospital (SJH), 8 Dublin, IrelandDepartment of Internal Medicine, St James’s Hospital (SJH), 8 Dublin, IrelandDepartment of Internal Medicine, St James’s Hospital (SJH), 8 Dublin, IrelandEnvo-Geo Environmental Geoinformatics, Cork, IrelandDepartment of Internal Medicine, St James’s Hospital (SJH), 8 Dublin, IrelandFor three cohorts (the elderly, socially deprived, and those with chronic disabling disease), the relationship between the concentrations of particulate matter (PM10), sulphur dioxide (SO2), or oxides of nitrogen (NOx) at the time of hospital admission and outcomes (30-day in-hospital mortality) were investigated All emergency admissions (90,423 episodes, recorded in 48,035 patients) between 2002 and 2015 were examined. PM10, SO2, and NOx daily levels from the hospital catchment area were correlated with the outcomes for the older admission cohort (>70 years), those of lower socio-economic status (SES), and with more disabling disease. Adjusted for acuity and complexity, the level of each pollutant on the day of admission independently predicted the 30-day mortality: for PM10–OR 1.11 (95% CI: 1.08, 1.15), SO2–1.20 (95% CI: 1.16, 1.24), and NOx–1.09 (1.06–1.13). For the older admission cohort (≥70 years), as admission day pollution increased (NOx quintiles) the 30-day mortality was higher in the elderly (14.2% vs. 11.3%: p < 0.001). Persons with a lower SES were at increased risk. Persons with more disabling disease also had worse outcomes on days with higher admission particulate matter (PM10 quintiles). Levels of pollutants on the day of admission of emergency medical admissions predicted 30-day hospital mortality.https://www.mdpi.com/2305-6304/5/4/27emergency medical admissionshigh risk cohortPM10SO2NOx |
| spellingShingle | Seán Cournane Richard Conway Declan Byrne Deirdre O’Riordan Seamus Coveney Bernard Silke High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission Toxics emergency medical admissions high risk cohort PM10 SO2 NOx |
| title | High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission |
| title_full | High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission |
| title_fullStr | High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission |
| title_full_unstemmed | High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission |
| title_short | High Risk Subgroups Sensitive to Air Pollution Levels Following an Emergency Medical Admission |
| title_sort | high risk subgroups sensitive to air pollution levels following an emergency medical admission |
| topic | emergency medical admissions high risk cohort PM10 SO2 NOx |
| url | https://www.mdpi.com/2305-6304/5/4/27 |
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