Isolation of Intact and Functional Melanosomes from the Retinal Pigment Epithelium.

Melanosomes of retinal pigment epithelium (RPE) have many vision supporting functions. Melanosome research would benefit from a method to isolate pure and characterized melanosomes. Sucrose gradient centrifugation is the most commonly used method for isolation of RPE melanosomes, but the isolated pr...

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Bibliographic Details
Main Authors: Laura Pelkonen, Mika Reinisalo, Emmanuelle Morin-Picardat, Heidi Kidron, Arto Urtti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4994940?pdf=render