The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study
The objective of this study was to evaluate the efficacy of the noojerone in patients with moderate Alzheimer disease and to compare obtained data with results of clinical trials of memantine. This was a 24-week open - label post-marketing clinical trial conducted in Department of Geriatric Psychiat...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2018-07-01
|
| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| Subjects: | |
| Online Access: | https://www.bekhterevreview.com/jour/article/view/53 |
| _version_ | 1826573119922372608 |
|---|---|
| author | N. M. Zalutskaya I. A. Beltceva N. G. Neznanov |
| author_facet | N. M. Zalutskaya I. A. Beltceva N. G. Neznanov |
| author_sort | N. M. Zalutskaya |
| collection | DOAJ |
| description | The objective of this study was to evaluate the efficacy of the noojerone in patients with moderate Alzheimer disease and to compare obtained data with results of clinical trials of memantine. This was a 24-week open - label post-marketing clinical trial conducted in Department of Geriatric Psychiatry St. Petersburg V.M. Bekhterev Psychoneurological Research Institute. Participants were 44 outpatients with moderate AD and Mini-Mental State Examination scores of 10-19 at start - point. This study have demonstrated efficacy in modifying course of AD and no significant deterioration activities of daily living and frequency and severity of behavioral symptoms, comparable with the results of memantine clinical trials. |
| first_indexed | 2024-03-12T03:48:36Z |
| format | Article |
| id | doaj.art-86e06f1f2b86482aa13735fa21023bc1 |
| institution | Directory Open Access Journal |
| issn | 2313-7053 2713-055X |
| language | Russian |
| last_indexed | 2025-03-14T12:37:51Z |
| publishDate | 2018-07-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj.art-86e06f1f2b86482aa13735fa21023bc12025-03-02T09:12:42ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2018-07-010410210953The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational studyN. M. Zalutskaya0I. A. Beltceva1N. G. Neznanov2Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. БехтереваСанкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. БехтереваСанкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. БехтереваThe objective of this study was to evaluate the efficacy of the noojerone in patients with moderate Alzheimer disease and to compare obtained data with results of clinical trials of memantine. This was a 24-week open - label post-marketing clinical trial conducted in Department of Geriatric Psychiatry St. Petersburg V.M. Bekhterev Psychoneurological Research Institute. Participants were 44 outpatients with moderate AD and Mini-Mental State Examination scores of 10-19 at start - point. This study have demonstrated efficacy in modifying course of AD and no significant deterioration activities of daily living and frequency and severity of behavioral symptoms, comparable with the results of memantine clinical trials.https://www.bekhterevreview.com/jour/article/view/53деменцияболезнь альцгеймерамемантиннооджеронкогнитивные функцииdementiaalzheimer diseasenoojeronememantine |
| spellingShingle | N. M. Zalutskaya I. A. Beltceva N. G. Neznanov The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева деменция болезнь альцгеймера мемантин нооджерон когнитивные функции dementia alzheimer disease noojerone memantine |
| title | The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study |
| title_full | The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study |
| title_fullStr | The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study |
| title_full_unstemmed | The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study |
| title_short | The dynamics of the cognitive and social functioning of patients with Alzheimer’s disease on therapy with antidementiv drugs: the results of observational study |
| title_sort | dynamics of the cognitive and social functioning of patients with alzheimer s disease on therapy with antidementiv drugs the results of observational study |
| topic | деменция болезнь альцгеймера мемантин нооджерон когнитивные функции dementia alzheimer disease noojerone memantine |
| url | https://www.bekhterevreview.com/jour/article/view/53 |
| work_keys_str_mv | AT nmzalutskaya thedynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy AT iabeltceva thedynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy AT ngneznanov thedynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy AT nmzalutskaya dynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy AT iabeltceva dynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy AT ngneznanov dynamicsofthecognitiveandsocialfunctioningofpatientswithalzheimersdiseaseontherapywithantidementivdrugstheresultsofobservationalstudy |