A rapid fluorescence assay for sphingosine-1-phosphate lyase enzyme activity
Sphingosine-1-phosphate (S1P) lyase (SPL) catalyzes the conversion of S1P to ethanolamine phosphate and hexadecenal. This enzyme plays diverse roles in physiology and disease and, thus, may be useful as a disease marker and/or drug target. Unfortunately, the radioisotope-based assay currently used t...
Main Authors: | Padmavathi Bandhuvula, Henrik Fyrst, Julie D. Saba |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-12-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752042927X |
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