An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience
<i>Background and Objectives</i>: There is a lack of data about the survival of patients after the implantation of sutureless relative to stented bioprostheses in middle-income settings. The objective of this study was to compare the survival of people with isolated severe aortic stenosi...
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MDPI AG
2023-05-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/6/1032 |
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| author | Marko Kaitovic Slobodan Micovic Ivan Nesic Tatjana Raickovic Jelena Dotlic Ivan Stojanovic Tatjana Gazibara |
| author_facet | Marko Kaitovic Slobodan Micovic Ivan Nesic Tatjana Raickovic Jelena Dotlic Ivan Stojanovic Tatjana Gazibara |
| author_sort | Marko Kaitovic |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: There is a lack of data about the survival of patients after the implantation of sutureless relative to stented bioprostheses in middle-income settings. The objective of this study was to compare the survival of people with isolated severe aortic stenosis after the implantation of sutureless and stented bioprostheses in a tertiary referral center in Serbia. <i>Materials and Methods</i>: This retrospective cohort study included all people treated for isolated severe aortic stenosis with sutureless and stented bioprostheses from 1 January 2018 to 1 July 2021 at the Institute for Cardiovascular Diseases “Dedinje”. Demographic, clinical, perioperative and postoperative data were extracted from the medical records. The follow-up lasted for a median of 2 years. <i>Results</i>: The study sample comprised a total of 238 people with a stented (conventional) bioprosthesis and 101 people with a sutureless bioprosthesis (Perceval). Over the follow-up, 13.9% of people who received the conventional and 10.9% of people who received the Perceval valve died (<i>p</i> = 0.400). No difference in the overall survival was observed (<i>p</i> = 0.797). The multivariate Cox proportional hazard model suggested that being older, having a higher preoperative EuroScore II, having a stroke over the follow-up period and having valve-related complications were independently associated with all-cause mortality over a median of 2 years after the bioprosthesis implantation. <i>Conclusions</i>: This research conducted in a middle-income country supports previous findings in high-income countries regarding the survival of people with sutureless and stented valves. Survival after bioprosthesis implantation should be monitored long-term to ensure optimum postoperative outcomes. |
| first_indexed | 2024-03-11T02:11:26Z |
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| id | doaj.art-86e88cfb0c8c49a1b3296260b615a5e4 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T02:11:26Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-86e88cfb0c8c49a1b3296260b615a5e42023-11-18T11:30:28ZengMDPI AGMedicina1010-660X1648-91442023-05-01596103210.3390/medicina59061032An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country ExperienceMarko Kaitovic0Slobodan Micovic1Ivan Nesic2Tatjana Raickovic3Jelena Dotlic4Ivan Stojanovic5Tatjana Gazibara6Cardiac Surgery Department, Institute for Cardiovascular Diseases “Dedinje”, 11040 Belgrade, SerbiaCardiac Surgery Department, Institute for Cardiovascular Diseases “Dedinje”, 11040 Belgrade, SerbiaCardiac Surgery Department, Institute for Cardiovascular Diseases “Dedinje”, 11040 Belgrade, SerbiaCardiac Surgery Department, Institute for Cardiovascular Diseases “Dedinje”, 11040 Belgrade, SerbiaClinic for Obstetrics and Gynecology, Clinical Center of Serbia, 11000 Belgrade, SerbiaCardiac Surgery Department, Institute for Cardiovascular Diseases “Dedinje”, 11040 Belgrade, SerbiaInstitute of Epidemiology, Faculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia<i>Background and Objectives</i>: There is a lack of data about the survival of patients after the implantation of sutureless relative to stented bioprostheses in middle-income settings. The objective of this study was to compare the survival of people with isolated severe aortic stenosis after the implantation of sutureless and stented bioprostheses in a tertiary referral center in Serbia. <i>Materials and Methods</i>: This retrospective cohort study included all people treated for isolated severe aortic stenosis with sutureless and stented bioprostheses from 1 January 2018 to 1 July 2021 at the Institute for Cardiovascular Diseases “Dedinje”. Demographic, clinical, perioperative and postoperative data were extracted from the medical records. The follow-up lasted for a median of 2 years. <i>Results</i>: The study sample comprised a total of 238 people with a stented (conventional) bioprosthesis and 101 people with a sutureless bioprosthesis (Perceval). Over the follow-up, 13.9% of people who received the conventional and 10.9% of people who received the Perceval valve died (<i>p</i> = 0.400). No difference in the overall survival was observed (<i>p</i> = 0.797). The multivariate Cox proportional hazard model suggested that being older, having a higher preoperative EuroScore II, having a stroke over the follow-up period and having valve-related complications were independently associated with all-cause mortality over a median of 2 years after the bioprosthesis implantation. <i>Conclusions</i>: This research conducted in a middle-income country supports previous findings in high-income countries regarding the survival of people with sutureless and stented valves. Survival after bioprosthesis implantation should be monitored long-term to ensure optimum postoperative outcomes.https://www.mdpi.com/1648-9144/59/6/1032aortic valve replacementstented bioprosthesissutureless bioprosthesisPerceval valvesurvivalmiddle-income country |
| spellingShingle | Marko Kaitovic Slobodan Micovic Ivan Nesic Tatjana Raickovic Jelena Dotlic Ivan Stojanovic Tatjana Gazibara An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience Medicina aortic valve replacement stented bioprosthesis sutureless bioprosthesis Perceval valve survival middle-income country |
| title | An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience |
| title_full | An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience |
| title_fullStr | An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience |
| title_full_unstemmed | An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience |
| title_short | An Analysis of Early Results after Valve Replacement in Isolated Aortic Valve Stenosis by Using Sutureless vs. Stented Bioprostheses: A Single-Center Middle-Income Country Experience |
| title_sort | analysis of early results after valve replacement in isolated aortic valve stenosis by using sutureless vs stented bioprostheses a single center middle income country experience |
| topic | aortic valve replacement stented bioprosthesis sutureless bioprosthesis Perceval valve survival middle-income country |
| url | https://www.mdpi.com/1648-9144/59/6/1032 |
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