Sugar signals from oral glucose transporters elicit cephalic-phase insulin release in mice

Abstract Cephalic-phase insulin release (CPIR) occurs before blood glucose increases after a meal. Although glucose is the most plausible cue to induce CPIR, peripheral sensory systems involved are not fully elucidated. We therefore examined roles of sweet sensing by a T1R3-dependent taste receptor...

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Bibliographic Details
Main Authors: Mitsuhito Takamori, Yoshihiro Mitoh, Kengo Horie, Masahiko Egusa, Takuya Miyawaki, Ryusuke Yoshida
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Physiological Sciences
Subjects:
Online Access:https://doi.org/10.1186/s12576-023-00875-3