Zinc in the Brain: Friend or Foe?

Zinc in the Brain: Friend or Foe?

Zinc is a trace metal ion in the central nervous system that plays important biological roles, such as in catalysis, structure, and regulation. It contributes to antioxidant function and the proper functioning of the immune system. In view of these characteristics of zinc, it plays an important role...

Full description

Bibliographic Details
Main Authors:	Seunghyuk Choi, Dae Ki Hong, Bo Young Choi, Sang Won Suh
Format:	Article
Language:	English
Published:	MDPI AG 2020-11-01
Series:	International Journal of Molecular Sciences
Subjects:	zinc physiology pathophysiology brain
Online Access:	https://www.mdpi.com/1422-0067/21/23/8941

Similar Items

Carvacrol Inhibits Expression of Transient Receptor Potential Melastatin 7 Channels and Alleviates Zinc Neurotoxicity Induced by Traumatic Brain Injury
by: Minwoo Lee, et al.
Published: (2022-11-01)

Pathophysiological Roles of Transient Receptor Potential (Trp) Channels and Zinc Toxicity in Brain Disease
by: Dae Ki Hong, et al.
Published: (2023-04-01)

The Protective Role of Glutathione on Zinc-Induced Neuron Death after Brain Injuries
by: Min Kyu Park, et al.
Published: (2023-02-01)

Serum Zinc and Long-Term Prognosis after Acute Traumatic Brain Injury with Intracranial Injury: A Multicenter Prospective Study
by: Ki Hong Kim, et al.
Published: (2022-11-01)

The Epistemology of Deep Brain Stimulation and Neuronal Pathophysiology
by: Erwin eMontgomery
Published: (2012-09-01)

Neutrophils in traumatic brain injury (TBI): friend or foe?
by: Yang-Wuyue Liu, et al.
Published: (2018-05-01)

Regulated regeneration of adipose tissue in lipodystrophic Agpat2-null mice partially ameliorates hepatic steatosis
by: Anil K. Agarwal, et al.
Published: (2024-04-01)

Engineered Mesenchymal Stem Cells Over-Expressing BDNF Protect the Brain from Traumatic Brain Injury-Induced Neuronal Death, Neurological Deficits, and Cognitive Impairments
by: Bo Young Choi, et al.
Published: (2023-03-01)

Zinc Signal in Brain Diseases
by: Stuart D. Portbury, et al.
Published: (2017-11-01)

Expression and Distribution of Free Zinc in Penile Erectile Tissue
by: Beom Seok Kang, et al.
Published: (2023-01-01)

URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease
by: Yoshiro Tanaka, et al.
Published: (2023-09-01)

Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
by: Qiang Chen, et al.
Published: (2021-11-01)

Neuroinflammation in Post-Ischemic Neurodegeneration of the Brain: Friend, Foe, or Both?
by: Ryszard Pluta, et al.
Published: (2021-04-01)

Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease
by: Ryo Ito, et al.
Published: (2024-04-01)

Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis
by: Xiao-Jun Tian, et al.
Published: (2020-05-01)

Impact of Zinc Transport Mechanisms on Embryonic and Brain Development
by: Jeremy Willekens, et al.
Published: (2022-06-01)

Tenascin-C: Friend or Foe in Lung Aging?
by: Sandrine Gremlich, et al.
Published: (2021-10-01)

Neuroinflammation: friend and foe for ischemic stroke
by: Richard L. Jayaraj, et al.
Published: (2019-07-01)

Iron, Copper, and Zinc Homeostasis: Physiology, Physiopathology, and Nanomediated Applications
by: Robert Szabo, et al.
Published: (2021-11-01)

Cerebellar deep brain stimulation for movement disorders
by: Chun-Hwei Tai, et al.
Published: (2022-12-01)

CD9 exacerbates pathological cardiac hypertrophy through regulating GP130/STAT3 signaling pathway
by: Yue Li, et al.
Published: (2023-11-01)

Comprehensive analysis of the relationship between xanthine oxidoreductase activity and chronic kidney disease
by: Yiyuan Zhang, et al.
Published: (2023-11-01)

A Drosophila model of diabetic neuropathy reveals a role of proteasome activity in the glia
by: Mari Suzuki, et al.
Published: (2023-06-01)

Moesin is an effector of tau-induced actin overstabilization, cell cycle activation, and neurotoxicity in Alzheimer’s disease
by: Adrian Beckmann, et al.
Published: (2023-03-01)

Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
by: Lu Ren, et al.
Published: (2023-01-01)

Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy
by: Yukako Ohyama, et al.
Published: (2022-11-01)

Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome
by: Katarzyna Siemienowicz, et al.
Published: (2020-06-01)

Endogenous Metabolic Modulators: Emerging Therapeutic Potential of Amino Acids
by: Michael J. Hamill, et al.
Published: (2020-10-01)

The role of estrogens at men. Part 1. General and developmental endocrinology, physiology and pathophysiology of estrogens at men
by: I. A. Tyuzikov, et al.
Published: (2015-02-01)

The role of estrogens at men. Part 1. General and developmental endocrinology, physiology and pathophysiology of estrogens at men
by: I. A. Tyuzikov, et al.
Published: (2015-02-01)

The Role of AhR in the Hallmarks of Brain Aging: Friend and Foe
by: Emmanuel S. Ojo, et al.
Published: (2021-10-01)

Changes in aggression and locomotor behaviors in response to zinc is accompanied by brain cell heterogeneity and metabolic and circadian dysregulation of the brain-liver axis
by: Fan Yu, et al.
Published: (2022-12-01)

Effects of Transient Receptor Potential Cation 5 (TRPC5) Inhibitor, NU6027, on Hippocampal Neuronal Death after Traumatic Brain Injury
by: Min Kyu Park, et al.
Published: (2020-11-01)

A Novel Zinc Chelator, 1H10, Ameliorates Experimental Autoimmune Encephalomyelitis by Modulating Zinc Toxicity and AMPK Activation
by: Bo Young Choi, et al.
Published: (2020-05-01)

Effects of zinc supplement on tumorigenic (MCF-7) and non-tumorigenic (MCF-10A) mammary epithelial cells under different oxygen conditions
by: Lee, Sze Yen
Published: (2013)

The Gut Microbiome in Anorexia Nervosa: Friend or Foe?
by: Ana Ghenciulescu, et al.
Published: (2021-01-01)

Zinc and Traumatic Brain Injury: From Chelation to Supplementation
by: Cathy W. Levenson
Published: (2020-08-01)

The Inhibition of Zinc Excitotoxicity and AMPK Phosphorylation by a Novel Zinc Chelator, 2G11, Ameliorates Neuronal Death Induced by Global Cerebral Ischemia
by: Dae Ki Hong, et al.
Published: (2022-11-01)

Mysterious sphingolipids: metabolic interrelationships at the center of pathophysiology
by: Rama Jamjoum, et al.
Published: (2024-01-01)

Phosphate depletion in insulin-insensitive skeletal muscle drives AMPD activation and sarcopenia in chronic kidney disease
by: Ana Andres-Hernando, et al.
Published: (2023-04-01)