Imaging in Lyme neuroborreliosis
Abstract Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among differential diagnoses when clinical manifestations from the nervous system...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2018-09-01
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| Series: | Insights into Imaging |
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| Online Access: | http://link.springer.com/article/10.1007/s13244-018-0646-x |
| _version_ | 1819064615976304640 |
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| author | Elisabeth S. Lindland Anne Marit Solheim Silje Andreassen Else Quist-Paulsen Randi Eikeland Unn Ljøstad Åse Mygland Ahmed Elsais Gro O. Nygaard Åslaug R. Lorentzen Hanne F. Harbo Mona K. Beyer |
| author_facet | Elisabeth S. Lindland Anne Marit Solheim Silje Andreassen Else Quist-Paulsen Randi Eikeland Unn Ljøstad Åse Mygland Ahmed Elsais Gro O. Nygaard Åslaug R. Lorentzen Hanne F. Harbo Mona K. Beyer |
| author_sort | Elisabeth S. Lindland |
| collection | DOAJ |
| description | Abstract Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among differential diagnoses when clinical manifestations from the nervous system occur. Radiculitis, meningitis and facial palsy are commonly encountered, while peripheral neuropathy, myelitis, meningoencephalitis and cerebral vasculitis are rarer manifestations of LNB. Cerebrospinal fluid (CSF) analysis and serology are key investigations in patient workup. The primary role of imaging is to rule out other reasons for the neurological symptoms. It is therefore important to know the diversity of possible imaging findings from the infection itself. There may be no imaging abnormality, or findings suggestive of neuritis, meningitis, myelitis, encephalitis or vasculitis. White matter lesions are not a prominent feature of LNB. Insight into LNB clinical presentation, laboratory test methods and spectrum of imaging pathology will aid in the multidisciplinary interaction that often is imperative to achieve an efficient patient workup and arrive at a correct diagnosis. This article can educate those engaged in imaging of the nervous system and serve as a comprehensive tool in clinical cases. Key Points • Diagnostic criteria for LNB emphasise exclusion of an alternative cause to the clinical symptoms. • MRI makes a crucial contribution in the diagnosis and follow-up of LNB. • MRI may have normal findings, or show neuritis, meningitis, myelitis, encephalitis or vasculitis. • White matter lesions are not a prominent feature of LNB. |
| first_indexed | 2024-12-21T15:33:24Z |
| format | Article |
| id | doaj.art-86eb51a312f84796a242a70fd1328447 |
| institution | Directory Open Access Journal |
| issn | 1869-4101 |
| language | English |
| last_indexed | 2024-12-21T15:33:24Z |
| publishDate | 2018-09-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Insights into Imaging |
| spelling | doaj.art-86eb51a312f84796a242a70fd13284472022-12-21T18:58:42ZengSpringerOpenInsights into Imaging1869-41012018-09-019583384410.1007/s13244-018-0646-xImaging in Lyme neuroborreliosisElisabeth S. Lindland0Anne Marit Solheim1Silje Andreassen2Else Quist-Paulsen3Randi Eikeland4Unn Ljøstad5Åse Mygland6Ahmed Elsais7Gro O. Nygaard8Åslaug R. Lorentzen9Hanne F. Harbo10Mona K. Beyer11Department of Radiology and Nuclear Medicine, Oslo University HospitalDepartment of Neurology, Sorlandet HospitalInstitute of Clinical Medicine, University of OsloInstitute of Clinical Medicine, University of OsloDepartment of Neurology, Sorlandet HospitalDepartment of Neurology, Sorlandet HospitalDepartment of Neurology, Sorlandet HospitalDepartment of Neurology, Oslo University HospitalDepartment of Neurology, Oslo University HospitalDepartment of Neurology, Sorlandet HospitalInstitute of Clinical Medicine, University of OsloDepartment of Radiology and Nuclear Medicine, Oslo University HospitalAbstract Lyme neuroborreliosis (LNB) is a tick-borne spirochetal infection with a broad spectrum of imaging pathology. For individuals who live in or have travelled to areas where ticks reside, LNB should be considered among differential diagnoses when clinical manifestations from the nervous system occur. Radiculitis, meningitis and facial palsy are commonly encountered, while peripheral neuropathy, myelitis, meningoencephalitis and cerebral vasculitis are rarer manifestations of LNB. Cerebrospinal fluid (CSF) analysis and serology are key investigations in patient workup. The primary role of imaging is to rule out other reasons for the neurological symptoms. It is therefore important to know the diversity of possible imaging findings from the infection itself. There may be no imaging abnormality, or findings suggestive of neuritis, meningitis, myelitis, encephalitis or vasculitis. White matter lesions are not a prominent feature of LNB. Insight into LNB clinical presentation, laboratory test methods and spectrum of imaging pathology will aid in the multidisciplinary interaction that often is imperative to achieve an efficient patient workup and arrive at a correct diagnosis. This article can educate those engaged in imaging of the nervous system and serve as a comprehensive tool in clinical cases. Key Points • Diagnostic criteria for LNB emphasise exclusion of an alternative cause to the clinical symptoms. • MRI makes a crucial contribution in the diagnosis and follow-up of LNB. • MRI may have normal findings, or show neuritis, meningitis, myelitis, encephalitis or vasculitis. • White matter lesions are not a prominent feature of LNB.http://link.springer.com/article/10.1007/s13244-018-0646-xLyme neuroborreliosisMRINeuritisMyelitisEncephalitis |
| spellingShingle | Elisabeth S. Lindland Anne Marit Solheim Silje Andreassen Else Quist-Paulsen Randi Eikeland Unn Ljøstad Åse Mygland Ahmed Elsais Gro O. Nygaard Åslaug R. Lorentzen Hanne F. Harbo Mona K. Beyer Imaging in Lyme neuroborreliosis Insights into Imaging Lyme neuroborreliosis MRI Neuritis Myelitis Encephalitis |
| title | Imaging in Lyme neuroborreliosis |
| title_full | Imaging in Lyme neuroborreliosis |
| title_fullStr | Imaging in Lyme neuroborreliosis |
| title_full_unstemmed | Imaging in Lyme neuroborreliosis |
| title_short | Imaging in Lyme neuroborreliosis |
| title_sort | imaging in lyme neuroborreliosis |
| topic | Lyme neuroborreliosis MRI Neuritis Myelitis Encephalitis |
| url | http://link.springer.com/article/10.1007/s13244-018-0646-x |
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