Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging

Abstract Aging is associated with widespread physiological changes, including skeletal muscle weakening, neuron system degeneration, hair loss, and skin wrinkling. Previous studies have identified numerous molecular biomarkers involved in these changes, but their regulatory mechanisms and functional...

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Bibliographic Details
Main Authors: Hwang-Yeol Lee, Yeonsu Jeon, Yeon Kyung Kim, Jae Young Jang, Yun Sung Cho, Jong Bhak, Kwang-Hyun Cho
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91811-1