Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips.

Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips.

The coronary artery ligation model in rodents mimics human myocardial infarction (MI). Normally mechanical ventilation and prolonged anesthesia period are needed. Recently, a method has been developed to create MI by popping-out the heart (without ventilation) followed by immediate suture ligation....

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Bibliographic Details
Main Authors: James N B M de Andrade, Junnan Tang, Michael Taylor Hensley, Adam Vandergriff, Jhon Cores, Eric Henry, Tyler A Allen, Thomas George Caranasos, Zegen Wang, Tianxia Zhang, Jinying Zhang, Ke Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4658059?pdf=render

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