Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance Mycobacterium tuberculosis peptides in human serum

Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance Mycobacterium tuberculosis peptides in human serum

Abstract Background Mycobacterium tuberculosis (Mtb) is the causative agent of Tuberculosis (TB), the number one cause of death due to an infectious disease. TB diagnosis is performed by microscopy, culture or PCR amplification of bacterial DNA, all of which require patient sputum or the biopsy of i...

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Bibliographic Details
Main Authors: Carolina Mehaffy, Karen M. Dobos, Payam Nahid, Nicole A. Kruh-Garcia
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Clinical Proteomics
Subjects:
MRM (Multiple Reaction Monitoring)
Mass Spectrometry
Tuberculosis
Exosomes
Mycobacterium tuberculosis
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12014-017-9156-y

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http://link.springer.com/article/10.1186/s12014-017-9156-y

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