Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up

Vertical ridge augmentation for long-term implant stability is difficult in severely resorbed areas. We examined the clinical, radiological, and histological outcomes of guided-bone regeneration using novel titanium-reinforced microporous expanded polytetrafluoroethylene (MP-ePTFE) membranes. Eighte...

Full description

Bibliographic Details
Main Authors: Jung-Gu Ji, Jung-A Yu, Seong-Ho Choi, Dong-Woon Lee
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/14/14/3828
_version_ 1797526729135226880
author Jung-Gu Ji
Jung-A Yu
Seong-Ho Choi
Dong-Woon Lee
author_facet Jung-Gu Ji
Jung-A Yu
Seong-Ho Choi
Dong-Woon Lee
author_sort Jung-Gu Ji
collection DOAJ
description Vertical ridge augmentation for long-term implant stability is difficult in severely resorbed areas. We examined the clinical, radiological, and histological outcomes of guided-bone regeneration using novel titanium-reinforced microporous expanded polytetrafluoroethylene (MP-ePTFE) membranes. Eighteen patients who underwent implant placement using a staged approach were enrolled (period: 2018–2019). Vertical ridge augmentation was performed in areas with vertical bone defects ≥4 mm. Twenty-six implant fixtures were placed in 14 patients. At implant placement six fixtures had relatively low stability. On cone-beam computed tomography, the average vertical changes were 4.2 ± 1.9 (buccal), 5.9 ± 2.7 (central), and 4.4 ± 2.8 mm (lingual) at six months after vertical ridge augmentation. Histomorphometric analyses revealed that the average proportions of new bone, residual bone substitute material, and soft tissue were 34.91 ± 11.61%, 7.16 ± 2.74%, and 57.93 ± 11.09%, respectively. Stable marginal bone levels were observed at 1-year post-loading. The residual bone graft material area was significantly lower in the exposed group (<i>p</i> = 0.003). There was no significant difference in the vertical height change in the buccal side between immediately after the augmentation procedure and the implant placement reentry time (<i>p</i> = 0.371). However, all implants functioned well regardless of the exposure during the observation period. Thus, vertical ridge augmentation around implants using titanium-reinforced MP-ePTFE membranes can be successful.
first_indexed 2024-03-10T09:33:32Z
format Article
id doaj.art-86f50e684e274e3e849ce0dd6719d68b
institution Directory Open Access Journal
issn 1996-1944
language English
last_indexed 2024-03-10T09:33:32Z
publishDate 2021-07-01
publisher MDPI AG
record_format Article
series Materials
spelling doaj.art-86f50e684e274e3e849ce0dd6719d68b2023-11-22T04:15:21ZengMDPI AGMaterials1996-19442021-07-011414382810.3390/ma14143828Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-UpJung-Gu Ji0Jung-A Yu1Seong-Ho Choi2Dong-Woon Lee3Department of Periodontology, Dental Hospital, Veterans Health Service Medical Center, Seoul 05368, KoreaDepartment of Periodontology, Dental Hospital, Veterans Health Service Medical Center, Seoul 05368, KoreaDepartment of Periodontology, College of Dentistry and Research Institute for Periodontal Regeneration, Yonsei University, Seoul 03722, KoreaDepartment of Periodontology, Dental Hospital, Veterans Health Service Medical Center, Seoul 05368, KoreaVertical ridge augmentation for long-term implant stability is difficult in severely resorbed areas. We examined the clinical, radiological, and histological outcomes of guided-bone regeneration using novel titanium-reinforced microporous expanded polytetrafluoroethylene (MP-ePTFE) membranes. Eighteen patients who underwent implant placement using a staged approach were enrolled (period: 2018–2019). Vertical ridge augmentation was performed in areas with vertical bone defects ≥4 mm. Twenty-six implant fixtures were placed in 14 patients. At implant placement six fixtures had relatively low stability. On cone-beam computed tomography, the average vertical changes were 4.2 ± 1.9 (buccal), 5.9 ± 2.7 (central), and 4.4 ± 2.8 mm (lingual) at six months after vertical ridge augmentation. Histomorphometric analyses revealed that the average proportions of new bone, residual bone substitute material, and soft tissue were 34.91 ± 11.61%, 7.16 ± 2.74%, and 57.93 ± 11.09%, respectively. Stable marginal bone levels were observed at 1-year post-loading. The residual bone graft material area was significantly lower in the exposed group (<i>p</i> = 0.003). There was no significant difference in the vertical height change in the buccal side between immediately after the augmentation procedure and the implant placement reentry time (<i>p</i> = 0.371). However, all implants functioned well regardless of the exposure during the observation period. Thus, vertical ridge augmentation around implants using titanium-reinforced MP-ePTFE membranes can be successful.https://www.mdpi.com/1996-1944/14/14/3828alveolar ridge augmentationbone regenerationdental implantation
spellingShingle Jung-Gu Ji
Jung-A Yu
Seong-Ho Choi
Dong-Woon Lee
Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
Materials
alveolar ridge augmentation
bone regeneration
dental implantation
title Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
title_full Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
title_fullStr Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
title_full_unstemmed Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
title_short Clinical, Radiographic, and Histomorphometric Evaluation of a Vertical Ridge Augmentation Procedure Using a Titanium-Reinforced Microporous Expanded Polytetrafluoroethylene Membrane: A Prospective Case Series with 1-Year Follow-Up
title_sort clinical radiographic and histomorphometric evaluation of a vertical ridge augmentation procedure using a titanium reinforced microporous expanded polytetrafluoroethylene membrane a prospective case series with 1 year follow up
topic alveolar ridge augmentation
bone regeneration
dental implantation
url https://www.mdpi.com/1996-1944/14/14/3828
work_keys_str_mv AT jungguji clinicalradiographicandhistomorphometricevaluationofaverticalridgeaugmentationprocedureusingatitaniumreinforcedmicroporousexpandedpolytetrafluoroethylenemembraneaprospectivecaseserieswith1yearfollowup
AT jungayu clinicalradiographicandhistomorphometricevaluationofaverticalridgeaugmentationprocedureusingatitaniumreinforcedmicroporousexpandedpolytetrafluoroethylenemembraneaprospectivecaseserieswith1yearfollowup
AT seonghochoi clinicalradiographicandhistomorphometricevaluationofaverticalridgeaugmentationprocedureusingatitaniumreinforcedmicroporousexpandedpolytetrafluoroethylenemembraneaprospectivecaseserieswith1yearfollowup
AT dongwoonlee clinicalradiographicandhistomorphometricevaluationofaverticalridgeaugmentationprocedureusingatitaniumreinforcedmicroporousexpandedpolytetrafluoroethylenemembraneaprospectivecaseserieswith1yearfollowup