Characterization of acid sphingomyelinase activity in human cerebrospinal fluid.

Characterization of acid sphingomyelinase activity in human cerebrospinal fluid.

<h4>Background</h4>As a key enzyme in sphingolipid metabolism, acid sphingomyelinase (ASM) is involved in the regulation of cell fate and signaling via hydrolysis of sphingomyelin to form ceramide. While increased activity of the lysosomal form has been associated with various pathologic...

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Bibliographic Details
Main Authors: Christiane Mühle, Hagen B Huttner, Silke Walter, Martin Reichel, Fabio Canneva, Piotr Lewczuk, Erich Gulbins, Johannes Kornhuber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23658784/?tool=EBI

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