Accuracy of whole slide image based image analysis is adversely affected by preanalytical factors such as stained tissue slide and paraffin block age

Accuracy of whole slide image based image analysis is adversely affected by preanalytical factors such as stained tissue slide and paraffin block age

Background: Personalized medicine and accurate quantification of tumor and biomarker expression have become the cornerstone of cancer diagnostics. This requires Quality Control (QC) of research tissue samples to confirm adequate targeted tumor tissue sampling. Digitalization of stained tissue slides...

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Bibliographic Details
Main Authors: Nada Shaker, Ruhani Sardana, Satoshi Hamasaki, David G. Nohle, Leona W. Ayers, Anil V. Parwani
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Journal of Pathology Informatics
Subjects:
Whole slide images
Tumor area identification
Slide age
Overall tumor percentage
AI algorithm
Online Access:http://www.sciencedirect.com/science/article/pii/S2153353922007155

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