Phototheranostics of Splenic Myeloid-Derived Suppressor Cells and Its Impact on Spleen Metabolism in Tumor-Bearing Mice

Phototheranostics of Splenic Myeloid-Derived Suppressor Cells and Its Impact on Spleen Metabolism in Tumor-Bearing Mice

(1) Background: MDSCs play an active role in the immune surveillance escape of cancer cells. Because MDSCs in mice are CD11b<sup>+</sup>Gr1<sup>+</sup>, near-infrared photoimmunotherapy (NIR-PIT) using the NIR dye IR700 conjugated to an MDSC-binding antibody provides an oppor...

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Bibliographic Details
Main Authors: James D. Barnett, Jiefu Jin, Marie-France Penet, Hisataka Kobayashi, Zaver M. Bhujwalla
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cancers
Subjects:
photoimmunotherapy
MDSCs
cancer
metabolism
spleen
Online Access:https://www.mdpi.com/2072-6694/14/15/3578

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