Can Bee Venom Be Used as Anticancer Agent in Modern Medicine?
Honey bee venom in its composition contains many biologically active peptides and enzymes that are effective in the fight against diseases of various etiologies. The history of the use of bee venom for medicinal purposes dates back thousands of years. There are many reports in the literature on the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/15/14/3714 |
| _version_ | 1797589904118513664 |
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| author | Agata Małek Maciej Strzemski Joanna Kurzepa Jacek Kurzepa |
| author_facet | Agata Małek Maciej Strzemski Joanna Kurzepa Jacek Kurzepa |
| author_sort | Agata Małek |
| collection | DOAJ |
| description | Honey bee venom in its composition contains many biologically active peptides and enzymes that are effective in the fight against diseases of various etiologies. The history of the use of bee venom for medicinal purposes dates back thousands of years. There are many reports in the literature on the pharmacological properties of bee venom and/or its main components, e.g., anti-arthritic, anti-inflammatory, anti-microbial or neuroprotective properties. In addition, both crude venom and melittin exhibit cytotoxic activity against a wide range of tumor cells, with significant anti-metastatic activity in pre-clinical studies. Due to the constantly increasing incidence of cancer, the development of new therapeutic strategies in oncology is a particular challenge for modern medicine. A review paper discusses the various properties of bee venom with an emphasis on its anticancer properties. For this purpose, the PubMed database was searched, and publications related to “bee”, “venom”, “cancer” from the last 10 years were selected. |
| first_indexed | 2024-03-11T01:12:44Z |
| format | Article |
| id | doaj.art-8702b74db9154d5682566d21a3b9f3f0 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T01:12:44Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-8702b74db9154d5682566d21a3b9f3f02023-11-18T18:43:06ZengMDPI AGCancers2072-66942023-07-011514371410.3390/cancers15143714Can Bee Venom Be Used as Anticancer Agent in Modern Medicine?Agata Małek0Maciej Strzemski1Joanna Kurzepa2Jacek Kurzepa3Department of Medical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, PolandDepartment of Analytical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, Poland1st Department of Radiology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, PolandDepartment of Medical Chemistry, Medical University of Lublin, Chodźki 4a, 20-093 Lublin, PolandHoney bee venom in its composition contains many biologically active peptides and enzymes that are effective in the fight against diseases of various etiologies. The history of the use of bee venom for medicinal purposes dates back thousands of years. There are many reports in the literature on the pharmacological properties of bee venom and/or its main components, e.g., anti-arthritic, anti-inflammatory, anti-microbial or neuroprotective properties. In addition, both crude venom and melittin exhibit cytotoxic activity against a wide range of tumor cells, with significant anti-metastatic activity in pre-clinical studies. Due to the constantly increasing incidence of cancer, the development of new therapeutic strategies in oncology is a particular challenge for modern medicine. A review paper discusses the various properties of bee venom with an emphasis on its anticancer properties. For this purpose, the PubMed database was searched, and publications related to “bee”, “venom”, “cancer” from the last 10 years were selected.https://www.mdpi.com/2072-6694/15/14/3714bee venommelittincancertumorapoptosis |
| spellingShingle | Agata Małek Maciej Strzemski Joanna Kurzepa Jacek Kurzepa Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? Cancers bee venom melittin cancer tumor apoptosis |
| title | Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? |
| title_full | Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? |
| title_fullStr | Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? |
| title_full_unstemmed | Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? |
| title_short | Can Bee Venom Be Used as Anticancer Agent in Modern Medicine? |
| title_sort | can bee venom be used as anticancer agent in modern medicine |
| topic | bee venom melittin cancer tumor apoptosis |
| url | https://www.mdpi.com/2072-6694/15/14/3714 |
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