A 2D GaAs-Based Photonic Crystal Biosensor for Malaria Detection
Gallium arsenide (GaAs) composite semi-conductive rods with an air background lattice act as the building blocks for the photonic crystal structure used of a biosensor. The study presents a biosensor of a two-rod nano-cavity for identifying distinct stages of plasmodium falciparum in red blood cell...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Taiwan Association of Engineering and Technology Innovation
2023-08-01
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| Series: | International Journal of Engineering and Technology Innovation |
| Subjects: | |
| Online Access: | https://ojs.imeti.org/index.php/IJETI/article/view/11660 |
| Summary: | Gallium arsenide (GaAs) composite semi-conductive rods with an air background lattice act as the building blocks for the photonic crystal structure used of a biosensor. The study presents a biosensor of a two-rod nano-cavity for identifying distinct stages of plasmodium falciparum in red blood cells (RBCs) in the early detection of malaria. The proposed biosensor enables the creation of a label-free biosensing environment in which optical and dispersion properties are investigated using plane wave expansion (PWE) and finite-difference time-domain (FDTD) techniques. The biosensor, with a sensing region for an analyte, is utilized to detect a change in refractive index to differentiate between normal RBCs and plasmodium falciparum-infected cells. The results show that the biosensor has a high sensitivity of 798.143 nm/RIU, a high Q-factor of 9881.926, a low detection limit (δ) of 222.4 × 10-6 RIU, a high FOM of 4496.079 RIU-1, and a compact area of 46.14 µm2.
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| ISSN: | 2223-5329 2226-809X |