New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples
A magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed for the extraction of nonsteroidal anti-inflamma...
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| Format: | Article |
| Language: | English |
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The Royal Society
2018-01-01
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| Series: | Royal Society Open Science |
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| Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171311 |
| _version_ | 1831652389373870080 |
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| author | Syed Fariq Fathullah Syed Yaacob Muhammad Afzal Kamboh Wan Aini Wan Ibrahim Sharifah Mohamad |
| author_facet | Syed Fariq Fathullah Syed Yaacob Muhammad Afzal Kamboh Wan Aini Wan Ibrahim Sharifah Mohamad |
| author_sort | Syed Fariq Fathullah Syed Yaacob |
| collection | DOAJ |
| description | A magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed for the extraction of nonsteroidal anti-inflammatory drugs (NSAIDs), namely, indoprofen (INP), ketoprofen (KTP), ibuprofen (IBP) and fenoprofen (FNP) from water samples prior to their HPLC-DAD determination. The newly synthesized MSp-TDI-βCD was comprehensibly characterized using FT-IR, XRD, SEM-EDX, BET and VSM analyses. The separation of selected NSAIDs on MSp-TDI-βCD from aqueous solution was simply achieved by applying an external magnetic field via a permanent magnet. The MSPE parameters affecting extraction performance, i.e. sorbent dosage, sample volume, extraction and desorption time, type of organic eluent and volume and solution pH were investigated and optimized. The proposed method showed linear range between 0.5 and 500 ng ml−1, low limit of detection at S/N = 3 (0.16–0.37 ng ml−1) and limit of quantification at S/N = 10 (0.53–1.22 ng ml−1). The inter-day (n = 15) and intra-day (n = 5) precision for the proposed methods given by relative standard deviation (RSD%) was in the range of 2.5–4.0 and 2.1–5.5, respectively. The extraction recoveries of NSAIDs from environmental samples (tap, drinking and river water) ranged from 92.5% to 123.6%, with satisfactory precision (RSD% less than 12.4%). |
| first_indexed | 2024-12-19T15:45:34Z |
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| id | doaj.art-870502f0e1854e6d80d75915e4ae333a |
| institution | Directory Open Access Journal |
| issn | 2054-5703 |
| language | English |
| last_indexed | 2024-12-19T15:45:34Z |
| publishDate | 2018-01-01 |
| publisher | The Royal Society |
| record_format | Article |
| series | Royal Society Open Science |
| spelling | doaj.art-870502f0e1854e6d80d75915e4ae333a2022-12-21T20:15:21ZengThe Royal SocietyRoyal Society Open Science2054-57032018-01-015710.1098/rsos.171311171311New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samplesSyed Fariq Fathullah Syed YaacobMuhammad Afzal KambohWan Aini Wan IbrahimSharifah MohamadA magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed for the extraction of nonsteroidal anti-inflammatory drugs (NSAIDs), namely, indoprofen (INP), ketoprofen (KTP), ibuprofen (IBP) and fenoprofen (FNP) from water samples prior to their HPLC-DAD determination. The newly synthesized MSp-TDI-βCD was comprehensibly characterized using FT-IR, XRD, SEM-EDX, BET and VSM analyses. The separation of selected NSAIDs on MSp-TDI-βCD from aqueous solution was simply achieved by applying an external magnetic field via a permanent magnet. The MSPE parameters affecting extraction performance, i.e. sorbent dosage, sample volume, extraction and desorption time, type of organic eluent and volume and solution pH were investigated and optimized. The proposed method showed linear range between 0.5 and 500 ng ml−1, low limit of detection at S/N = 3 (0.16–0.37 ng ml−1) and limit of quantification at S/N = 10 (0.53–1.22 ng ml−1). The inter-day (n = 15) and intra-day (n = 5) precision for the proposed methods given by relative standard deviation (RSD%) was in the range of 2.5–4.0 and 2.1–5.5, respectively. The extraction recoveries of NSAIDs from environmental samples (tap, drinking and river water) ranged from 92.5% to 123.6%, with satisfactory precision (RSD% less than 12.4%).https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171311sporopolleninmagnetic nanoparticlesβ-cyclodextrinnsaidsmagnetic solid-phase extraction |
| spellingShingle | Syed Fariq Fathullah Syed Yaacob Muhammad Afzal Kamboh Wan Aini Wan Ibrahim Sharifah Mohamad New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples Royal Society Open Science sporopollenin magnetic nanoparticles β-cyclodextrin nsaids magnetic solid-phase extraction |
| title | New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples |
| title_full | New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples |
| title_fullStr | New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples |
| title_full_unstemmed | New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples |
| title_short | New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples |
| title_sort | new sporopollenin based β cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid phase extraction of nonsteroidal anti inflammatory drugs from water samples |
| topic | sporopollenin magnetic nanoparticles β-cyclodextrin nsaids magnetic solid-phase extraction |
| url | https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.171311 |
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