Introduction of a Capillary Gel Electrophoresis-Based Workflow for Biotherapeutics Characterization: Size, Charge, and N-Glycosylation Variant Analysis of Bamlanivimab, an Anti-SARS-CoV-2 Product

Introduction of a Capillary Gel Electrophoresis-Based Workflow for Biotherapeutics Characterization: Size, Charge, and N-Glycosylation Variant Analysis of Bamlanivimab, an Anti-SARS-CoV-2 Product

Coronavirus Disease 2019 (COVID-19) is a major public health problem worldwide with 5–10% hospitalization and 2–3% global mortality rates at the time of this publication. The disease is caused by a betacoronavirus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The receptor-bind...

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Bibliographic Details
Main Authors: Miklos Szabo, Daniel Sarkozy, Marton Szigeti, Robert Farsang, Zsofia Kardos, Adam Kozma, Eszter Csanky, Doo Soo Chung, Zoltan Szekanecz, Andras Guttman
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
capillary electrophoresis
bamlanivimab
anti-SARS-CoV-2
product characterization
N-glycans
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.839374/full

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