Primary cutaneous histoplasmosis in a HIV-positive individual
A 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary l...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2010-01-01
|
Series: | Journal of Global Infectious Diseases |
Subjects: | |
Online Access: | http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=Vasudevan |
_version_ | 1818897677074563072 |
---|---|
author | Biju Vasudevan Bahal Ashish Sagar Amitabh A P Mohanty |
author_facet | Biju Vasudevan Bahal Ashish Sagar Amitabh A P Mohanty |
author_sort | Biju Vasudevan |
collection | DOAJ |
description | A 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary lymphadenopathy. There was history of local injury on the face 6 months prior to the development of symptoms. Skin biopsy revealed multiple round to oval spores with surrounding halo intracellularly, confirming the diagnosis of cutaneous histoplasmosis. No systemic involvement was detected on further investigations. The patient responded to oral antifungals in a short duration, confirming the local nature of the presentation. This is probably the first time in the literature that a primary cutaneous manifestation of histoplasmosis is being described in an immunocompromised individual. |
first_indexed | 2024-12-19T19:19:58Z |
format | Article |
id | doaj.art-87143826e78542238320e430d7c2ec77 |
institution | Directory Open Access Journal |
issn | 0974-777X |
language | English |
last_indexed | 2024-12-19T19:19:58Z |
publishDate | 2010-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Journal of Global Infectious Diseases |
spelling | doaj.art-87143826e78542238320e430d7c2ec772022-12-21T20:09:01ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2010-01-012211211510.4103/0974-777X.62884Primary cutaneous histoplasmosis in a HIV-positive individualBiju VasudevanBahal AshishSagar AmitabhA P MohantyA 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary lymphadenopathy. There was history of local injury on the face 6 months prior to the development of symptoms. Skin biopsy revealed multiple round to oval spores with surrounding halo intracellularly, confirming the diagnosis of cutaneous histoplasmosis. No systemic involvement was detected on further investigations. The patient responded to oral antifungals in a short duration, confirming the local nature of the presentation. This is probably the first time in the literature that a primary cutaneous manifestation of histoplasmosis is being described in an immunocompromised individual.http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=VasudevanHistoplasmosisFungusHuman immunodeficiency virusItraconazole |
spellingShingle | Biju Vasudevan Bahal Ashish Sagar Amitabh A P Mohanty Primary cutaneous histoplasmosis in a HIV-positive individual Journal of Global Infectious Diseases Histoplasmosis Fungus Human immunodeficiency virus Itraconazole |
title | Primary cutaneous histoplasmosis in a HIV-positive individual |
title_full | Primary cutaneous histoplasmosis in a HIV-positive individual |
title_fullStr | Primary cutaneous histoplasmosis in a HIV-positive individual |
title_full_unstemmed | Primary cutaneous histoplasmosis in a HIV-positive individual |
title_short | Primary cutaneous histoplasmosis in a HIV-positive individual |
title_sort | primary cutaneous histoplasmosis in a hiv positive individual |
topic | Histoplasmosis Fungus Human immunodeficiency virus Itraconazole |
url | http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=Vasudevan |
work_keys_str_mv | AT bijuvasudevan primarycutaneoushistoplasmosisinahivpositiveindividual AT bahalashish primarycutaneoushistoplasmosisinahivpositiveindividual AT sagaramitabh primarycutaneoushistoplasmosisinahivpositiveindividual AT apmohanty primarycutaneoushistoplasmosisinahivpositiveindividual |