Primary cutaneous histoplasmosis in a HIV-positive individual

A 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary l...

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Main Authors: Biju Vasudevan, Bahal Ashish, Sagar Amitabh, A P Mohanty
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Journal of Global Infectious Diseases
Subjects:
Online Access:http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=Vasudevan
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author Biju Vasudevan
Bahal Ashish
Sagar Amitabh
A P Mohanty
author_facet Biju Vasudevan
Bahal Ashish
Sagar Amitabh
A P Mohanty
author_sort Biju Vasudevan
collection DOAJ
description A 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary lymphadenopathy. There was history of local injury on the face 6 months prior to the development of symptoms. Skin biopsy revealed multiple round to oval spores with surrounding halo intracellularly, confirming the diagnosis of cutaneous histoplasmosis. No systemic involvement was detected on further investigations. The patient responded to oral antifungals in a short duration, confirming the local nature of the presentation. This is probably the first time in the literature that a primary cutaneous manifestation of histoplasmosis is being described in an immunocompromised individual.
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spelling doaj.art-87143826e78542238320e430d7c2ec772022-12-21T20:09:01ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2010-01-012211211510.4103/0974-777X.62884Primary cutaneous histoplasmosis in a HIV-positive individualBiju VasudevanBahal AshishSagar AmitabhA P MohantyA 31-year-old human immunodeficiency virus-positive male who presented to the Dermatology Outpatient Department with complaints of red, raised lesions on the face of 2 weeks duration was, on examination, found to have multiple papulonodular lesions on the face with associated cervical and axillary lymphadenopathy. There was history of local injury on the face 6 months prior to the development of symptoms. Skin biopsy revealed multiple round to oval spores with surrounding halo intracellularly, confirming the diagnosis of cutaneous histoplasmosis. No systemic involvement was detected on further investigations. The patient responded to oral antifungals in a short duration, confirming the local nature of the presentation. This is probably the first time in the literature that a primary cutaneous manifestation of histoplasmosis is being described in an immunocompromised individual.http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=VasudevanHistoplasmosisFungusHuman immunodeficiency virusItraconazole
spellingShingle Biju Vasudevan
Bahal Ashish
Sagar Amitabh
A P Mohanty
Primary cutaneous histoplasmosis in a HIV-positive individual
Journal of Global Infectious Diseases
Histoplasmosis
Fungus
Human immunodeficiency virus
Itraconazole
title Primary cutaneous histoplasmosis in a HIV-positive individual
title_full Primary cutaneous histoplasmosis in a HIV-positive individual
title_fullStr Primary cutaneous histoplasmosis in a HIV-positive individual
title_full_unstemmed Primary cutaneous histoplasmosis in a HIV-positive individual
title_short Primary cutaneous histoplasmosis in a HIV-positive individual
title_sort primary cutaneous histoplasmosis in a hiv positive individual
topic Histoplasmosis
Fungus
Human immunodeficiency virus
Itraconazole
url http://www.jgid.org/article.asp?issn=0974-777X;year=2010;volume=2;issue=2;spage=112;epage=115;aulast=Vasudevan
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AT bahalashish primarycutaneoushistoplasmosisinahivpositiveindividual
AT sagaramitabh primarycutaneoushistoplasmosisinahivpositiveindividual
AT apmohanty primarycutaneoushistoplasmosisinahivpositiveindividual