Consensus Statement on Proton Therapy for Prostate Cancer

Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective...

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Main Authors: Curtis M. Bryant, MD, MPH, Randal H. Henderson, MD, MBA, R. Charles Nichols, MD, William M. Mendenhall, MD, Bradford S. Hoppe, MD, MPH, Carlos E. Vargas, MD, Thomas B. Daniels, MD, C. Richard Choo, MD, Rahul R. Parikh, MD, Huan Giap, MD, PhD, Jerry D. Slater, MD, Neha Vapiwala, MD, William Barrett, MD, Akash Nanda, MD, PhD, Mark V. Mishra, MD, Seungtaek Choi, MD, Jay J. Liao, MD, Nancy P. Mendenhall, MD, the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group
Format: Article
Language:English
Published: Particle Therapy Co-operative Group 2021-04-01
Series:International Journal of Particle Therapy
Subjects:
Online Access:https://theijpt.org/doi/pdf/10.14338/IJPT-20-00031.1
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author Curtis M. Bryant, MD, MPH
Randal H. Henderson, MD, MBA
R. Charles Nichols, MD
William M. Mendenhall, MD
Bradford S. Hoppe, MD, MPH
Carlos E. Vargas, MD
Thomas B. Daniels, MD
C. Richard Choo, MD
Rahul R. Parikh, MD
Huan Giap, MD, PhD
Jerry D. Slater, MD
Neha Vapiwala, MD
William Barrett, MD
Akash Nanda, MD, PhD
Mark V. Mishra, MD
Seungtaek Choi, MD
Jay J. Liao, MD
Nancy P. Mendenhall, MD
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group
author_facet Curtis M. Bryant, MD, MPH
Randal H. Henderson, MD, MBA
R. Charles Nichols, MD
William M. Mendenhall, MD
Bradford S. Hoppe, MD, MPH
Carlos E. Vargas, MD
Thomas B. Daniels, MD
C. Richard Choo, MD
Rahul R. Parikh, MD
Huan Giap, MD, PhD
Jerry D. Slater, MD
Neha Vapiwala, MD
William Barrett, MD
Akash Nanda, MD, PhD
Mark V. Mishra, MD
Seungtaek Choi, MD
Jay J. Liao, MD
Nancy P. Mendenhall, MD
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group
author_sort Curtis M. Bryant, MD, MPH
collection DOAJ
description Proton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.
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spelling doaj.art-871926a9f47046e99a4987b232eaa4872024-04-16T16:07:59ZengParticle Therapy Co-operative GroupInternational Journal of Particle Therapy2331-51802021-04-018211610.14338/IJPT-20-00031.1i2331-5180-8-2-1Consensus Statement on Proton Therapy for Prostate CancerCurtis M. Bryant, MD, MPH0Randal H. Henderson, MD, MBA1R. Charles Nichols, MD2William M. Mendenhall, MD3Bradford S. Hoppe, MD, MPH4Carlos E. Vargas, MD5Thomas B. Daniels, MD6C. Richard Choo, MD7Rahul R. Parikh, MD8Huan Giap, MD, PhD9Jerry D. Slater, MD10Neha Vapiwala, MD11William Barrett, MD12Akash Nanda, MD, PhD13Mark V. Mishra, MD14Seungtaek Choi, MD15Jay J. Liao, MD16Nancy P. Mendenhall, MD17the Genitourinary Subcommittee of the Particle Therapy Co-Operative GroupDepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USADepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USADepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USADepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USADepartment of Radiation Oncology, Mayo Clinic, Jacksonville, FL, USADepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USADepartment of Radiation Oncology, Mayo Clinic, Phoenix, AZ, USADepartment of Radiation Oncology, Mayo Clinic Rochester, Rochester, MN, USADepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USADepartment of Radiation Oncology, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL, USADepartment of Radiation Oncology, Loma Linda University, Loma Linda, CA, USADepartment of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USADepartment of Radiation Oncology, University of Cincinnati, Cincinnati, OH, USADepartment of Radiation Oncology, Orlando Health, Orlando, FL, USADepartment of Radiation Oncology, University of Maryland School of Medicine, Baltimore, MD, USADepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USADepartment of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USADepartment of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USAProton therapy is a promising but controversial treatment in the management of prostate cancer. Despite its dosimetric advantages when compared with photon radiation therapy, its increased cost to patients and insurers has raised questions regarding its value. Multiple prospective and retrospective studies have been published documenting the efficacy and safety of proton therapy for patients with localized prostate cancer and for patients requiring adjuvant or salvage pelvic radiation after surgery. The Particle Therapy Co-Operative Group (PTCOG) Genitourinary Subcommittee intends to address current proton therapy indications, advantages, disadvantages, and cost effectiveness. We will also discuss the current landscape of clinical trials. This consensus report can be used to guide clinical practice and research directions.https://theijpt.org/doi/pdf/10.14338/IJPT-20-00031.1prostate cancerradiation therapyproton therapyparticle therapy
spellingShingle Curtis M. Bryant, MD, MPH
Randal H. Henderson, MD, MBA
R. Charles Nichols, MD
William M. Mendenhall, MD
Bradford S. Hoppe, MD, MPH
Carlos E. Vargas, MD
Thomas B. Daniels, MD
C. Richard Choo, MD
Rahul R. Parikh, MD
Huan Giap, MD, PhD
Jerry D. Slater, MD
Neha Vapiwala, MD
William Barrett, MD
Akash Nanda, MD, PhD
Mark V. Mishra, MD
Seungtaek Choi, MD
Jay J. Liao, MD
Nancy P. Mendenhall, MD
the Genitourinary Subcommittee of the Particle Therapy Co-Operative Group
Consensus Statement on Proton Therapy for Prostate Cancer
International Journal of Particle Therapy
prostate cancer
radiation therapy
proton therapy
particle therapy
title Consensus Statement on Proton Therapy for Prostate Cancer
title_full Consensus Statement on Proton Therapy for Prostate Cancer
title_fullStr Consensus Statement on Proton Therapy for Prostate Cancer
title_full_unstemmed Consensus Statement on Proton Therapy for Prostate Cancer
title_short Consensus Statement on Proton Therapy for Prostate Cancer
title_sort consensus statement on proton therapy for prostate cancer
topic prostate cancer
radiation therapy
proton therapy
particle therapy
url https://theijpt.org/doi/pdf/10.14338/IJPT-20-00031.1
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