Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency
Abstract Background Radiography is useful to determine left atrial (LA) size when echocardiography is not available. Recently, the authors have described Radiographic Left Atrial Dimension (RLAD) as a new radiographic measurement to assess LA size. The objective of this study was to assess the clini...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | Irish Veterinary Journal |
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| Online Access: | http://link.springer.com/article/10.1186/s13620-019-0152-6 |
| _version_ | 1818116512828882944 |
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| author | Xavier Sánchez Salguero David Prandi Francisco Llabrés-Díaz Edgar G. Manzanilla Llorenç Badiella Claudio Bussadori |
| author_facet | Xavier Sánchez Salguero David Prandi Francisco Llabrés-Díaz Edgar G. Manzanilla Llorenç Badiella Claudio Bussadori |
| author_sort | Xavier Sánchez Salguero |
| collection | DOAJ |
| description | Abstract Background Radiography is useful to determine left atrial (LA) size when echocardiography is not available. Recently, the authors have described Radiographic Left Atrial Dimension (RLAD) as a new radiographic measurement to assess LA size. The objective of this study was to assess the clinical usefulness of 2 new radiographic measurements to detect and quantify left atrial enlargement (LAE) compared to RLAD and using left atrium to aortic root (LA/Ao) ratio as gold standard. These new measurements, bronchus-to-spine (Br-Spine) and RLAD-to-spine (RLAD-Spine) may be more precise in cases were LA boundaries are not well defined. Fifty dogs, 25 with and 25 without LAE were recruited. Reference LA/Ao ratio was assessed by 2D echocardiography and LAE was considered if LA/Ao > 1.6. Br-spine was measured as a straight vertical line from the main stem bronchus to the ventral border of the vertebra situated immediately dorsal to the heart base. RLAD-Spine was measured from RLAD endpoint perpendicularly to spine. The correlation of RLAD, Br-Spine and RLAD-Spine methods with LA/Ao and their sensitivity and specificity for detecting LAE were calculated. Receiver Operating Characteristic (ROC) curves were used to estimate the optimal cut-off for each method. Results Correlations between Br-Spine, RLAD-Spine, RLAD and LA/Ao ratio were − 0.66, − 0.76 and 0.89 respectively (P < 0.001). Sensitivity at the optimal cut-off values for detecting LAE were 32.0, 64.0 and 96.0%, respectively. Specificity was 96.0% in all cases. Conclusion Br-Spine and RLAD-Spine were less sensitive radiographic measurements than RLAD in detecting LAE in dogs. Both Br-Spine and RLAD-Spine may not be good alternatives to RLAD. |
| first_indexed | 2024-12-11T04:23:42Z |
| format | Article |
| id | doaj.art-871cb4ff72c4463e91766a7c67a40f47 |
| institution | Directory Open Access Journal |
| issn | 2046-0481 |
| language | English |
| last_indexed | 2024-12-11T04:23:42Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Irish Veterinary Journal |
| spelling | doaj.art-871cb4ff72c4463e91766a7c67a40f472022-12-22T01:21:02ZengBMCIrish Veterinary Journal2046-04812019-11-017211410.1186/s13620-019-0152-6Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiencyXavier Sánchez Salguero0David Prandi1Francisco Llabrés-Díaz2Edgar G. Manzanilla3Llorenç Badiella4Claudio Bussadori5Animal Science Department, Escola Tècnica Superior d’Enginyeria Agrària, Universitat de LleidaBetulia Veterinary ClinicRoyal Veterinary CollegeAnimal and Grassland Research Centre, TeagascServei d’Estadística Aplicada, Universitat Autònoma de BarcelonaClínica Veterinaria Gran SassoAbstract Background Radiography is useful to determine left atrial (LA) size when echocardiography is not available. Recently, the authors have described Radiographic Left Atrial Dimension (RLAD) as a new radiographic measurement to assess LA size. The objective of this study was to assess the clinical usefulness of 2 new radiographic measurements to detect and quantify left atrial enlargement (LAE) compared to RLAD and using left atrium to aortic root (LA/Ao) ratio as gold standard. These new measurements, bronchus-to-spine (Br-Spine) and RLAD-to-spine (RLAD-Spine) may be more precise in cases were LA boundaries are not well defined. Fifty dogs, 25 with and 25 without LAE were recruited. Reference LA/Ao ratio was assessed by 2D echocardiography and LAE was considered if LA/Ao > 1.6. Br-spine was measured as a straight vertical line from the main stem bronchus to the ventral border of the vertebra situated immediately dorsal to the heart base. RLAD-Spine was measured from RLAD endpoint perpendicularly to spine. The correlation of RLAD, Br-Spine and RLAD-Spine methods with LA/Ao and their sensitivity and specificity for detecting LAE were calculated. Receiver Operating Characteristic (ROC) curves were used to estimate the optimal cut-off for each method. Results Correlations between Br-Spine, RLAD-Spine, RLAD and LA/Ao ratio were − 0.66, − 0.76 and 0.89 respectively (P < 0.001). Sensitivity at the optimal cut-off values for detecting LAE were 32.0, 64.0 and 96.0%, respectively. Specificity was 96.0% in all cases. Conclusion Br-Spine and RLAD-Spine were less sensitive radiographic measurements than RLAD in detecting LAE in dogs. Both Br-Spine and RLAD-Spine may not be good alternatives to RLAD.http://link.springer.com/article/10.1186/s13620-019-0152-6DogLeft atrial sizeMitral valve diseaseRadiographic measurementRLAD |
| spellingShingle | Xavier Sánchez Salguero David Prandi Francisco Llabrés-Díaz Edgar G. Manzanilla Llorenç Badiella Claudio Bussadori Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency Irish Veterinary Journal Dog Left atrial size Mitral valve disease Radiographic measurement RLAD |
| title | Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| title_full | Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| title_fullStr | Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| title_full_unstemmed | Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| title_short | Heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| title_sort | heart to spine measurements to detect left atrial enlargement in dogs with mitral insufficiency |
| topic | Dog Left atrial size Mitral valve disease Radiographic measurement RLAD |
| url | http://link.springer.com/article/10.1186/s13620-019-0152-6 |
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