Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system
Axon guidance is proposed to act through a combination of long- and short-range attractive and repulsive cues. The ligand-receptor pair, Netrin (Net) and Frazzled (Fra) (DCC, Deleted in Colorectal Cancer, in vertebrates), is recognized as the prototypical effector of chemoattraction, with roles in b...
Main Authors: | Orkun Akin, S Lawrence Zipursky |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2016-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/20762 |
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