Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

Evidence for conserved DNA and histone H3 methylation reprogramming in mouse, bovine and rabbit zygotes

<p>Abstract</p> <p>Background</p> <p>In mammals the parental genomes are epigenetically reprogrammed after fertilization. This reprogramming includes a rapid demethylation of the paternal (sperm-derived) chromosomes prior to DNA replication in zygotes. Such active DNA d...

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Bibliographic Details
Main Authors: Lepikhov Konstantin, Zakhartchenko Valeri, Hao Ru, Yang Feikun, Wrenzycki Christine, Niemann Heiner, Wolf Eckhard, Walter Joern
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/1/1/8

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