The Unexpected Role of Calcium‐Activated Potassium Channels: Limitation of NO‐Induced Arterial Relaxation

The Unexpected Role of Calcium‐Activated Potassium Channels: Limitation of NO‐Induced Arterial Relaxation

BackgroundMultiple studies have shown that an NO‐induced activation of vascular smooth muscle BK channels contributes to the NO‐evoked dilation in many blood vessels. In vivo, NO is released continuously. NO attenuates vessel constrictions and, therefore, exerts an anticontractile effect. It is unkn...

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Bibliographic Details
Main Authors: Johannes Schmid, Bettina Müller, David Heppeler, Dina Gaynullina, Mario Kassmann, Hristo Gagov, Mitko Mladenov, Maik Gollasch, Rudolf Schubert
Format: Article
Language:English
Published: Wiley 2018-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
artery
NO
potassium channels
vascular tone regulation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.007808

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